The African American Outreach Core (AAOC) supports the aims of the Washington University Knight Alzheimer's Disease Research Center. The AAOC strives to increase the diversity of the Knight ADRC participant pool by recruiting African Americans (AAs), the largest minority group in the metropolitan St. Louis area. The AAOC assists in the recruitment and retention of African American participants to support all Knight ADRC studies and projects, defines and addresses barriers to participation; evaluates and makes recommendations in the home setting to demented patients and their families, and develops and provides minority outreach programs targeted at potential participants, their families, and healthcare providers who serve the AA community. In this renewal, the AAOC will continue to lead recruitment and retention of AA participants in close collaboration with Knight ADRC components, particularly by being fully integrated with the Clinical and Outreach Recruitment and Education (OREC) Cores and the African American Advisory Board. Our goal is to ensure that of the new participants enrolled in the Knight ADRC Clinical Core, at least 20% are AA to maintain the percentage of AA participants in the Knight ADRC Clinical Core at 17% or higher through the next five years. The AAOC will continue to conduct home-based cognitive assessments to provide a dementia diagnosis to AA elderly and to address any barriers to participation in our research studies. In this renewal, we have the additional Aim to screen, address, and modify mobility and/or safety concerns (e.g., transportation and impaired driving, risk for falls, medication compliance) in our home dementia assessment program.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
5P50AG005681-36
Application #
9697257
Study Section
Special Emphasis Panel (ZAG1)
Project Start
Project End
2021-04-30
Budget Start
2019-05-01
Budget End
2020-04-30
Support Year
36
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Washington University
Department
Type
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Jansen, Willemijn J; Ossenkoppele, Rik; Tijms, Betty M et al. (2018) Association of Cerebral Amyloid-? Aggregation With Cognitive Functioning in Persons Without Dementia. JAMA Psychiatry 75:84-95
Allison, Samantha; Babulal, Ganesh M; Stout, Sarah H et al. (2018) Alzheimer Disease Biomarkers and Driving in Clinically Normal Older Adults: Role of Spatial Navigation Abilities. Alzheimer Dis Assoc Disord 32:101-106
Gordon, Brian A; Blazey, Tyler M; Su, Yi et al. (2018) Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study. Lancet Neurol 17:241-250
Islam, Jyoti; Zhang, Yanqing (2018) Brain MRI analysis for Alzheimer's disease diagnosis using an ensemble system of deep convolutional neural networks. Brain Inform 5:2
Burke, Shanna L; Hu, Tianyan; Fava, Nicole M et al. (2018) Sex differences in the development of mild cognitive impairment and probable Alzheimer's disease as predicted by hippocampal volume or white matter hyperintensities. J Women Aging :1-25
Stout, Sarah H; Babulal, Ganesh M; Ma, Chunyu et al. (2018) Driving cessation over a 24-year period: Dementia severity and cerebrospinal fluid biomarkers. Alzheimers Dement 14:610-616
Roe, Catherine M; Ances, Beau M; Head, Denise et al. (2018) Incident cognitive impairment: longitudinal changes in molecular, structural and cognitive biomarkers. Brain 141:3233-3248
La Joie, Renaud; Bejanin, Alexandre; Fagan, Anne M et al. (2018) Associations between [18F]AV1451 tau PET and CSF measures of tau pathology in a clinical sample. Neurology 90:e282-e290
Kirson, Noam Y; Scott Andrews, J; Desai, Urvi et al. (2018) Patient Characteristics and Outcomes Associated with Receiving an Earlier Versus Later Diagnosis of Probable Alzheimer's Disease. J Alzheimers Dis 61:295-307
Ihara, Ryoko; Vincent, Benjamin D; Baxter, Michael R et al. (2018) Relative neuron loss in hippocampal sclerosis of aging and Alzheimer's disease. Ann Neurol 84:741-753

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