The African American Outreach Core (AAOC) supports the aims of the Washington University Knight Alzheimer's Disease Research Center. The AAOC strives to increase the diversity of the Knight ADRC participant pool by recruiting African Americans (AAs), the largest minority group in the metropolitan St. Louis area. The AAOC assists in the recruitment and retention of African American participants to support all Knight ADRC studies and projects, defines and addresses barriers to participation; evaluates and makes recommendations in the home setting to demented patients and their families, and develops and provides minority outreach programs targeted at potential participants, their families, and healthcare providers who serve the AA community. In this renewal, the AAOC will continue to lead recruitment and retention of AA participants in close collaboration with Knight ADRC components, particularly by being fully integrated with the Clinical and Outreach Recruitment and Education (OREC) Cores and the African American Advisory Board. Our goal is to ensure that of the new participants enrolled in the Knight ADRC Clinical Core, at least 20% are AA to maintain the percentage of AA participants in the Knight ADRC Clinical Core at 17% or higher through the next five years. The AAOC will continue to conduct home-based cognitive assessments to provide a dementia diagnosis to AA elderly and to address any barriers to participation in our research studies. In this renewal, we have the additional Aim to screen, address, and modify mobility and/or safety concerns (e.g., transportation and impaired driving, risk for falls, medication compliance) in our home dementia assessment program.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
5P50AG005681-36
Application #
9697257
Study Section
Special Emphasis Panel (ZAG1)
Project Start
Project End
2021-04-30
Budget Start
2019-05-01
Budget End
2020-04-30
Support Year
36
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Washington University
Department
Type
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Schaffert, Jeff; LoBue, Christian; White, Charles L et al. (2018) Traumatic brain injury history is associated with an earlier age of dementia onset in autopsy-confirmed Alzheimer's disease. Neuropsychology 32:410-416
Kamara, Dennis M; Gangishetti, Umesh; Gearing, Marla et al. (2018) Cerebral Amyloid Angiopathy: Similarity in African-Americans and Caucasians with Alzheimer's Disease. J Alzheimers Dis 62:1815-1826
Ramsey, Christine M; Gnjidic, Danijela; Agogo, George O et al. (2018) Longitudinal patterns of potentially inappropriate medication use following incident dementia diagnosis. Alzheimers Dement (N Y) 4:1-10
Schindler, Suzanne E; Sutphen, Courtney L; Teunissen, Charlotte et al. (2018) Upward drift in cerebrospinal fluid amyloid ? 42 assay values for more than 10 years. Alzheimers Dement 14:62-70
Su, Yi; Flores, Shaney; Hornbeck, Russ C et al. (2018) Utilizing the Centiloid scale in cross-sectional and longitudinal PiB PET studies. Neuroimage Clin 19:406-416
Lewczuk, Piotr; Riederer, Peter; O'Bryant, Sid E et al. (2018) Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry. World J Biol Psychiatry 19:244-328
Blue, Elizabeth E; Bis, Joshua C; Dorschner, Michael O et al. (2018) Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project. Dement Geriatr Cogn Disord 45:1-17
Kaur, Antarpreet; Edland, Steven D; Peavy, Guerry M (2018) The MoCA-Memory Index Score: An Efficient Alternative to Paragraph Recall for the Detection of Amnestic Mild Cognitive Impairment. Alzheimer Dis Assoc Disord 32:120-124
Joseph-Mathurin, Nelly; Su, Yi; Blazey, Tyler M et al. (2018) Utility of perfusion PET measures to assess neuronal injury in Alzheimer's disease. Alzheimers Dement (Amst) 10:669-677
Rao, Shuquan; Ghani, Mahdi; Guo, Zhiyun et al. (2018) An APOE-independent cis-eSNP on chromosome 19q13.32 influences tau levels and late-onset Alzheimer's disease risk. Neurobiol Aging 66:178.e1-178.e8

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