Abstract

The Center for Alzheimer's Disease Research (CADR) is a multi- disciplinary unit based at the College of Physicians and Surgeons of Columbia University and involving the Schools of Medicine, Public Health, Nursing and Arts and Sciences. It also has major components at the Burke Rehabilitation Hospital, Cornell University School of Medicine, The Harlem Hospital Center and the New York State Psychiatric Institute. The CADR maintains a well-characterize population of patients with Alzheimer's Disease (AD) as well as a large community based population of normal elderly. It provides diagnostic services, serves as a resource for tissue, cells and DNA from AD and control patients, and attempts to educated both health care providers and the community about AD. Its major research avenues are epidemiological, cell biological and molecular biological with developing research in caregiving. Based in Manhattan, the CADR serves a multi-racial, multi-ethnic community with sizable number of minority patients.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
3P50AG008702-09S1
Application #
2549349
Study Section
Special Emphasis Panel (ZAG1-BJS-3 (J4))
Project Start
1989-09-29
Project End
1999-05-31
Budget Start
1997-07-01
Budget End
1998-05-31
Support Year
9
Fiscal Year
1997
Total Cost
Indirect Cost

  Institution

Name
Columbia University (N.Y.)
Department
Pathology
Type
Schools of Medicine
DUNS #
167204994
City
New York
State
NY
Country
United States
Zip Code
10032

  Publications

Gallagher, Damien; Kiss, Alex; Lanctot, Krista L et al. (2018) Toward Prevention of Mild Cognitive Impairment in Older Adults With Depression: An Observational Study of Potentially Modifiable Risk Factors. J Clin Psychiatry 80:
Barnes, Josephine; Bartlett, Jonathan W; Wolk, David A et al. (2018) Disease Course Varies According to Age and Symptom Length in Alzheimer's Disease. J Alzheimers Dis 64:631-642
Burke, Shanna L; Maramaldi, Peter; Cadet, Tamara et al. (2018) Decreasing hazards of Alzheimer's disease with the use of antidepressants: mitigating the risk of depression and apolipoprotein E. Int J Geriatr Psychiatry 33:200-211
Qian, Winnie; Fischer, Corinne E; Schweizer, Tom A et al. (2018) Association Between Psychosis Phenotype and APOE Genotype on the Clinical Profiles of Alzheimer's Disease. Curr Alzheimer Res 15:187-194
Gallagher, Damien; Kiss, Alex; Lanctot, Krista et al. (2018) Depression and Risk of Alzheimer Dementia: A Longitudinal Analysis to Determine Predictors of Increased Risk among Older Adults with Depression. Am J Geriatr Psychiatry 26:819-827
Haaksma, Miriam L; Calderón-Larrañaga, Amaia; Olde Rikkert, Marcel G M et al. (2018) Cognitive and functional progression in Alzheimer disease: A prediction model of latent classes. Int J Geriatr Psychiatry 33:1057-1064
Bravo, Francisca Vaz; Da Silva, Jorge; Chan, Robin Barry et al. (2018) Phospholipase D functional ablation has a protective effect in an Alzheimer's disease Caenorhabditis elegans model. Sci Rep 8:3540
Ramsey, Christine M; Gnjidic, Danijela; Agogo, George O et al. (2018) Longitudinal patterns of potentially inappropriate medication use following incident dementia diagnosis. Alzheimers Dement (N Y) 4:1-10
Grivel, Margaux M; Leong, Wei; Masucci, Michael D et al. (2018) Impact of lifetime traumatic experiences on suicidality and likelihood of conversion in a cohort of individuals at clinical high-risk for psychosis. Schizophr Res 195:549-553
Hadjichrysanthou, Christoforos; McRae-McKee, Kevin; Evans, Stephanie et al. (2018) Potential Factors Associated with Cognitive Improvement of Individuals Diagnosed with Mild Cognitive Impairment or Dementia in Longitudinal Studies. J Alzheimers Dis 66:587-600

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