The Administrative Core of the Mayo Alzheimer's Disease Research Center will be responsible for the overall management of the Center. It will provide fiscal management, scientific direction, accountability, and communication with the National Alzheimer Coordinating Center and with other Alzheimer's Disease Centers. The ADRC will continue to pursue the scientific themes of the previous grant cycle, focusing on early detection of AD, particularly in the mild cognitive impairment (MCI) stage, and also focusing on non-AD dementias. The center will strive to expand AD research within the entire institution and will promote AD and non-AD dementia research nationally and internationally. The Core will oversee the pilot project program. The Core will have an Internal Steering Committee headed by the Center Director, and this Committee will oversee the scientific, personnel and fiscal issues of the Center. The Committee will also make the final judgment with regard to the awarding of pilot projects. The Core will continue with its ExternalAdvisory Committee, and this group will meet on an annual basis, alternating between Rochester, MN, and Jacksonville, FL. The Administrative Core will oversee the interactions among the cores and projects and will also integrate activities between Rochester, MN, and Jacksonville, FL. The Center will continue to provide relevant data to the National Alzheimer's Coordinating Center and will be compliant with the Uniform Data Set requirements. The Center Director and the staff will be responsible for compliance with the training requirements for key personnel as outlined by the Mayo Foundation, and all activities will be HIPAA compliant. The Director will communicate with the National Institute on Aging and provide annual progress reports.

Public Health Relevance

(Seeinstructions): The Administrative Core of the ADRC oversees the overall function of the Center. The Core coordinates the activities of the two sites and integrates the activities of the cores and the projects to accomplish the scientific goals of the Center.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
5P50AG016574-13
Application #
8288750
Study Section
Special Emphasis Panel (ZAG1)
Project Start
Project End
Budget Start
2011-07-01
Budget End
2012-04-30
Support Year
13
Fiscal Year
2011
Total Cost
$141,988
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
006471700
City
Rochester
State
MN
Country
United States
Zip Code
55905
Kasanuki, Koji; Ross, Owen A; DeTure, Michael A et al. (2018) Relationships between lewy and tau pathologies in 375 consecutive non-Alzheimer's olfactory bulbs. Mov Disord 33:333-334
Tachibana, Masaya; Yamazaki, Yu; Liu, Chia-Chen et al. (2018) Pericyte implantation in the brain enhances cerebral blood flow and reduces amyloid-? pathology in amyloid model mice. Exp Neurol 300:13-21
Guerreiro, Rita; Ross, Owen A; Kun-Rodrigues, Celia et al. (2018) Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study. Lancet Neurol 17:64-74
Deelchand, Dinesh K; Kantarci, Kejal; Öz, Gülin (2018) Improved localization, spectral quality, and repeatability with advanced MRS methodology in the clinical setting. Magn Reson Med 79:1241-1250
Levendowski, Daniel J; St Louis, Erik K; Strambi, Luigi Ferini et al. (2018) Comparison of EMG power during sleep from the submental and frontalis muscles. Nat Sci Sleep 10:431-437
Whitwell, Jennifer L; Graff-Radford, Jonathan; Tosakulwong, Nirubol et al. (2018) [18 F]AV-1451 clustering of entorhinal and cortical uptake in Alzheimer's disease. Ann Neurol 83:248-257
Allen, Mariet; Wang, Xue; Burgess, Jeremy D et al. (2018) Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases. Alzheimers Dement 14:352-366
Stricker, Nikki H; Lundt, Emily S; Edwards, Kelly K et al. (2018) Comparison of PC and iPad administrations of the Cogstate Brief Battery in the Mayo Clinic Study of Aging: assessing cross-modality equivalence of computerized neuropsychological tests. Clin Neuropsychol :1-25
Kaur, Antarpreet; Edland, Steven D; Peavy, Guerry M (2018) The MoCA-Memory Index Score: An Efficient Alternative to Paragraph Recall for the Detection of Amnestic Mild Cognitive Impairment. Alzheimer Dis Assoc Disord 32:120-124
Bove, Riley M; Patrick, Ellis; Aubin, Cristin McCabe et al. (2018) Reproductive period and epigenetic modifications of the oxidative phosphorylation pathway in the human prefrontal cortex. PLoS One 13:e0199073

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