Abstract

The Clinical, Cognitive, and Analytical Core will provide management of human studies, maintenance of a shared database, and statistical oversight for Projects I, II, and III. These activities include recmiting, screening, consent and enrollment of study participants; coordinating scheduling laboratory tests, neurocognitive tests, transcranial Doppler ultrasonography and brain imaging; and database management and statistical analysis. Establishing these functions in a Core assures continuity of recruitment and procedures, cost savings, quality sample collection, and data processing.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
4P50AG044170-05
Application #
9134031
Study Section
Special Emphasis Panel (ZRG1)
Project Start
Project End
Budget Start
2016-06-01
Budget End
2017-05-31
Support Year
5
Fiscal Year
2016
Total Cost
Indirect Cost

  Institution

Name
Mayo Clinic, Rochester
Department
Type
DUNS #
006471700
City
Rochester
State
MN
Country
United States
Zip Code
55905

  Publications

Wennberg, Alexandra M V; Hagen, Clinton E; Machulda, Mary M et al. (2018) The association between peripheral total IGF-1, IGFBP-3, and IGF-1/IGFBP-3 and functional and cognitive outcomes in the Mayo Clinic Study of Aging. Neurobiol Aging 66:68-74
Chandrashekar, Pranav; Fender, Erin Amanda; Zack, Chad J et al. (2018) Sex-stratified analysis of national trends and outcomes in isolated tricuspid valve surgery. Open Heart 5:e000719
Cintron, Dahima; Lahr, Brian D; Bailey, Kent R et al. (2018) Effects of oral versus transdermal menopausal hormone treatments on self-reported sleep domains and their association with vasomotor symptoms in recently menopausal women enrolled in the Kronos Early Estrogen Prevention Study (KEEPS). Menopause 25:145-153
Chan, Parco; Saleem, Mahwesh; Herrmann, Nathan et al. (2018) Ceramide Accumulation Is Associated with Declining Verbal Memory in Coronary Artery Disease Patients: An Observational Study. J Alzheimers Dis 64:1235-1246
Wennberg, Alexandra M V; Hagen, Clinton E; Petersen, Ronald C et al. (2018) Trajectories of plasma IGF-1, IGFBP-3, and their ratio in the Mayo Clinic Study of Aging. Exp Gerontol 106:67-73
Wennberg, Alexandra M V; Lesnick, Timothy G; Schwarz, Christopher G et al. (2018) Longitudinal Association Between Brain Amyloid-Beta and Gait in the Mayo Clinic Study of Aging. J Gerontol A Biol Sci Med Sci 73:1244-1250
Rocca, Walter A (2018) The future burden of Parkinson's disease. Mov Disord 33:8-9
Miller, Virginia M; Kling, Juliana M; Files, Julia A et al. (2018) What's in a name: are menopausal ""hot flashes"" a symptom of menopause or a manifestation of neurovascular dysregulation? Menopause 25:700-703
Beckman, J P; Camp, J J; Lahr, B D et al. (2018) Pregnancy history, coronary artery calcification and bone mineral density in menopausal women. Climacteric 21:53-59
Kattah, Andrea G; Suarez, Maria L G; Milic, Natasa et al. (2018) Hormone therapy and urine protein excretion: a multiracial cohort study, systematic review, and meta-analysis. Menopause 25:625-634

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