Overall We will establish an Alzheimer's Disease Research Center (ADRC) at Stanford University to serve as a shared resource to facilitate and enhance multidisciplinary and interdisciplinary research in Alzheimer's disease and related disorders. Our mission is to specialize in the collection, analysis and dissemination of data sets that are relevant to two common neurodegenerative illnesses, Alzheimer's disease and Parkinson's disease. The new Stanford ADRC will emphasize particular strengths in neuroimmunity and synapse biology, as well as strengths in imaging, clinical assessment and clinical research, biostatistics, and caregiver outreach. Outreach activities will focus specificaly on underserved urban Hispanic/Latino and American Indian communities. To accomplish these goals, we will establish core resources for human studies; make available biospecimens and biomarker data; provide structural and functional neuroimaging; maintain an administrative structure and consultative resources appropriate for these goals; provide community-based outreach and educational programs and research participation opportunities; support Center-sponsored research projects and pilot projects on these disorders; and support national efforts to understand disease mechanisms and find effective forms of therapy and prevention.

Public Health Relevance

We will establish an Alzheimer's Disease Research Center (ADRC) at Stanford University for new research collaborations that advance knowledge about, and aid in the prevention and treatment of Alzheimer's disease, Parkinson's disease, and related disorders. The Stanford ADRC will study healthy older adults and patients at early stages of their illness, followed over time. We are particularly interested in how the immune system affects the process of these disorders and the relation between changes in nerve synapses and disease progression.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Specialized Center (P50)
Project #
1P50AG047366-01A1
Application #
8849310
Study Section
Special Emphasis Panel (ZAG1)
Program Officer
Phelps, Creighton H
Project Start
2015-07-01
Project End
2020-04-30
Budget Start
2015-07-01
Budget End
2016-04-30
Support Year
1
Fiscal Year
2015
Total Cost
Indirect Cost
Name
Stanford University
Department
Neurology
Type
Schools of Medicine
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94304
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