Abstract

The CIDEIM clinical core is involved in recruiting, diagnosing, treating and following patients' with tegumentary leishmaniasis in southwestern Colombia. Its responsibilities include enrollment of patients, screening for compliance and follow-up potential, and categorization of patients as to eligibility. As part of diagnosis, it completes standardized clinical histories, and obtains the necessary samples for confirmation of Leishmania infection. It is also involved in treatment of patients and follows them to assess drug efficacy as well as secondary effects. Finally, together with the biometry core, it schedules patients for follow-up visits. This core is essential for the development of all projects that involve human subjects.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Specialized Center (P50)
Project #
5P50AI030603-02
Application #
3791593
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
1992
Total Cost
Indirect Cost

  Institution

Name
University of Valle
Department
Type
DUNS #
City
Cali
State
Country
Colombia
Zip Code

  Publications

Guarin, Nora; Palma, Gloria I; Pirmez, Claude et al. (2006) Comparative immunohistological analysis of the Montenegro skin test reaction in asymptomatic infection and in acute and chronic cutaneous leishmaniasis. Biomedica 26 Suppl 1:38-48
Travi, Bruno L; Tabares, Carlos Javier; Cadena, Horacio (2006) Leishmania (Viannia) braziliensis infection in two Colombian dogs: a note on infectivity for sand flies and response to treatment. Biomedica 26 Suppl 1:249-53
Rojas, Carlos A; Weigle, Kristen A; Barrera, Lena et al. (2002) Surveillance and screening of American cutaneous leishmaniasis by Colombian primary health care workers using a clinical prediction rule. Trans R Soc Trop Med Hyg 96:405-10
Weigle, Kristen A; Labrada, Luz Angela; Lozano, Caterin et al. (2002) PCR-based diagnosis of acute and chronic cutaneous leishmaniasis caused by Leishmania (Viannia). J Clin Microbiol 40:601-6
Saravia, Nancy Gore; Weigle, Kristen; Navas, Claudia et al. (2002) Heterogeneity, geographic distribution, and pathogenicity of serodemes of Leishmania viannia in Colombia. Am J Trop Med Hyg 66:738-44
Martinez, J E; Valderrama, L; Gama, V et al. (2000) Clonal diversity in the expression and stability of the metastatic capability of Leishmania guyanensis in the golden hamster. J Parasitol 86:792-9
Montoya-Lerma, J; Cadena, H; Segura, I et al. (1999) Association of Lutzomyia columbiana (Diptera: Psychodidae) with a leishmaniasis focus in Colombia due to species of the Leishmania mexicana complex. Mem Inst Oswaldo Cruz 94:277-83
Fernandes, O; Catanho, M P; Segura, I et al. (1999) Minicircle variable region probes for characterization of Leishmania (Viannia) species. J Parasitol 85:563-8
Saravia, N G; Segura, I; Holguin, A F et al. (1998) Epidemiologic, genetic, and clinical associations among phenotypically distinct populations of Leishmania (Viannia) in Colombia. Am J Trop Med Hyg 59:86-94
Osorio, Y; Gonzalez, S J; Gama, V L et al. (1998) Reinfection in American cutaneous leishmaniasis: evaluation of clinical outcomes in the hamster model. Mem Inst Oswaldo Cruz 93:353-6

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