Six of the individual research projects in this SCOR require the services of a Molecular Biology Core. The services include oligonucleotide synthesis and purification, plasmid preparations, and DNA amplification.

Project Start
Project End
Budget Start
Budget End
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Rosloniec, Edward F; Whittington, Karen B; He, Xiaowen et al. (2004) Collagen-induced arthritis mediated by HLA-DR1 (*0101) and HLA-DR4 (*0401). Am J Med Sci 327:169-79
Nanki, T; Lipsky, P E (2001) Stimulation of T-Cell activation by CXCL12/stromal cell derived factor-1 involves a G-protein mediated signaling pathway. Cell Immunol 214:145-54
Hayashida, K; Nanki, T; Girschick, H et al. (2001) Synovial stromal cells from rheumatoid arthritis patients attract monocytes by producing MCP-1 and IL-8. Arthritis Res 3:118-26
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Nanki, T; Lipsky, P E (2000) Lack of correlation between chemokine receptor and T(h)1/T(h)2 cytokine expression by individual memory T cells. Int Immunol 12:1659-67
Hayashida, K; Shimaoka, Y; Ochi, T et al. (2000) Rheumatoid arthritis synovial stromal cells inhibit apoptosis and up-regulate Bcl-xL expression by B cells in a CD49/CD29-CD106-dependent mechanism. J Immunol 164:1110-6
He, X; Stuart, J M (1999) Prostaglandin E2 selectively inhibits human CD4+ T cells secreting low amounts of both IL-2 and IL-4. J Immunol 163:6173-9
Brezinschek, R I; Oppenheimer-Marks, N; Lipsky, P E (1999) Activated T cells acquire endothelial cell surface determinants during transendothelial migration. J Immunol 162:1677-84
Davis, L S; Lipsky, P E (1998) Disordered differentiation of memory T cells in rheumatoid arthritis. Rev Rhum Engl Ed 65:291-6
Oppenheimer-Marks, N; Brezinschek, R I; Mohamadzadeh, M et al. (1998) Interleukin 15 is produced by endothelial cells and increases the transendothelial migration of T cells In vitro and in the SCID mouse-human rheumatoid arthritis model In vivo. J Clin Invest 101:1261-72

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