Abstract

This program will be directed by Gail Mahady (Res. Asst. Prof., Ph.D. 1991 in pharmacognosy, UIC) and Jan Engle (Clinical Assoc. Prof. Of Pharmacy, D. Pharm. 1985, UIC). Its major aim is to strengthen graduate and postgraduate training programs in pharmacognosy in order to provide a significant number of scientists able to address issues such as the quality, safety, and efficacy of botanical supplements. Curricula will be developed, and interactive Internet-based learning programs devised. Important biological, chemical, and pharmacological data will be collected from the literature for a number of medicinally important plants and assembled to provide a useful database. There will be an emphasis on botanicals relevant to women's health.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Complementary & Alternative Medicine (NCCAM)
Type
Specialized Center (P50)
Project #
5P50AT000155-04
Application #
6603606
Study Section
Special Emphasis Panel (ZRG1)
Project Start
2002-08-01
Project End
2003-07-31
Budget Start
Budget End
Support Year
4
Fiscal Year
2002
Total Cost
Indirect Cost

  Institution

Name
University of Illinois at Chicago
Department
Type
DUNS #
121911077
City
Chicago
State
IL
Country
United States
Zip Code
60612

  Publications

Hajirahimkhan, Atieh; Mbachu, Obinna; Simmler, Charlotte et al. (2018) Estrogen Receptor (ER) Subtype Selectivity Identifies 8-Prenylapigenin as an ER? Agonist from Glycyrrhiza inflata and Highlights the Importance of Chemical and Biological Authentication. J Nat Prod 81:966-975
Liu, Yang; Zhang, Yu; Chen, Shao-Nong et al. (2018) The influence of natural deep eutectic solvents on bioactive natural products: studying interactions between a hydrogel model and Schisandra chinensis metabolites. Fitoterapia 127:212-219
Liu, Yang; Friesen, J Brent; McAlpine, James B et al. (2018) Natural Deep Eutectic Solvents: Properties, Applications, and Perspectives. J Nat Prod 81:679-690
Rue, Emily A; Rush, Michael D; van Breemen, Richard B (2018) Procyanidins: a comprehensive review encompassing structure elucidation via mass spectrometry. Phytochem Rev 17:1-16
Simmler, Charlotte; Graham, James G; Chen, Shao-Nong et al. (2018) Integrated analytical assets aid botanical authenticity and adulteration management. Fitoterapia 129:401-414
Rush, Michael D; Walker, Elisabeth M; Prehna, Gerd et al. (2017) Development of a Magnetic Microbead Affinity Selection Screen (MagMASS) Using Mass Spectrometry for Ligands to the Retinoid X Receptor-?. J Am Soc Mass Spectrom 28:479-485
Dietz, Birgit M; Chen, Shao-Nong; Alvarenga, René F Ramos et al. (2017) DESIGNER Extracts as Tools to Balance Estrogenic and Chemopreventive Activities of Botanicals for Women's Health. J Nat Prod 80:2284-2294
Phansalkar, Rasika S; Simmler, Charlotte; Bisson, Jonathan et al. (2017) Evolution of Quantitative Measures in NMR: Quantum Mechanical qHNMR Advances Chemical Standardization of a Red Clover (Trifolium pratense) Extract. J Nat Prod 80:634-647
Li, Guannan; Simmler, Charlotte; Chen, Luying et al. (2017) Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents. Eur J Pharm Sci 109:182-190
Nikoli?, Dejan (2017) CASMI 2016: A manual approach for dereplication of natural products using tandem mass spectrometry. Phytochem Lett 21:292-296

Showing the most recent 10 out of 192 publications