The proposed post-doctoral tobacco research training program builds on an existing, highly successful Interdisciplinary Doctoral Training Program in Tumor Biology, predoctoral and postdoctoral training programs in Pharmacology, and a newly peer-reviewed and funded Cancer Prevention and control training component of the Tumor Biology Training Program. A focus of the new training program will be to recruit trainees from a consistently large, outstanding, and multi-disciplinary pool of qualified applicants with the M.D., M.D./Ph.D. or Ph.D. degrees in order to prepare them for patient- and population-based translational research in tobacco control. Each trainee will be supported for two years in the training program. The trainees will select a primary research mentor, based on their predoctoral research, course work and/or current research interests. Co-mentors will be assigned to each trainee to insure multi-disciplinary collaborations among mentors.
The specific aims are: 1. To recruit and select two post-doctoral trainees per year for a transdisciplinary tobacco research post-doctoral program, with particular attention paid to recruiting women and minorities. 2. To integrate and expand existing training programs at GUMC to create an educational curriculum for post-doctoral trainees, with particular emphasis on the theme of the TTURC (bio-behavioral basis of tobacco use). 3. To provide outstanding mentoring experiences for post-doctoral trainees, including involvement on research projects, as well as clinical and laboratory activities as appropriate. 4. To facilitate the career development of post-doctoral trainees through submission of pilot project and research grant applications. The training integrates multi-disciplinary faculty from the Lombardi Cancer Center (LCC) Programs in Cancer Prevention and Control and Cancer Genetics, as well as the Department of Pharmacology and the Georgetown Grace Dorney Institute on Tobacco and Health, and the National Institutes of Health. This new training program initiative will be co-led by Dr. Jon Kerner, Associate Director of the Lombardi Cancer Center and Control Research Program, Dr. Kenneth Keller, Professor of Pharmacology, and Dr. Janet Audrain, Assistant Professor of Psychiatry.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center (P50)
Project #
5P50CA084718-05
Application #
6661419
Study Section
Special Emphasis Panel (ZCA1)
Project Start
2002-09-30
Project End
2003-09-29
Budget Start
Budget End
Support Year
5
Fiscal Year
2002
Total Cost
Indirect Cost
Name
Georgetown University
Department
Type
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057
Hsu, Ping-Ching; Lan, Renny S; Brasky, Theodore M et al. (2017) Metabolomic profiles of current cigarette smokers. Mol Carcinog 56:594-606
Hsu, Ping-Ching; Lan, Renny S; Brasky, Theodore M et al. (2017) Menthol Smokers: Metabolomic Profiling and Smoking Behavior. Cancer Epidemiol Biomarkers Prev 26:51-60
Weng, Daniel Y; Chen, Jinguo; Taslim, Cenny et al. (2016) Persistent alterations of gene expression profiling of human peripheral blood mononuclear cells from smokers. Mol Carcinog 55:1424-37
Song, Min-Ae; Marian, Catalin; Brasky, Theodore M et al. (2016) Chemical and toxicological characteristics of conventional and low-TSNA moist snuff tobacco products. Toxicol Lett 245:68-77
Schnoll, Robert A; Goelz, Patricia M; Veluz-Wilkins, Anna et al. (2015) Long-term nicotine replacement therapy: a randomized clinical trial. JAMA Intern Med 175:504-11
David, Sean P; Strong, David R; Leventhal, Adam M et al. (2013) Influence of a dopamine pathway additive genetic efficacy score on smoking cessation: results from two randomized clinical trials of bupropion. Addiction 108:2202-11
Bough, K J; Lerman, C; Rose, J E et al. (2013) Biomarkers for smoking cessation. Clin Pharmacol Ther 93:526-38
Wang, Y-J; Huang, P; Ung, A et al. (2012) Reduced expression of the ? opioid receptor in some, but not all, brain regions in mice with OPRM1 A112G. Neuroscience 205:178-84
Perkins, Kenneth A; Parzynski, Craig; Mercincavage, Melissa et al. (2012) Is self-efficacy for smoking abstinence a cause of, or a reflection on, smoking behavior change? Exp Clin Psychopharmacol 20:56-62
Conklin, Cynthia A; Parzynski, Craig S; Salkeld, Ronald P et al. (2012) Cue reactivity as a predictor of successful abstinence initiation among adult smokers. Exp Clin Psychopharmacol 20:473-8

Showing the most recent 10 out of 148 publications