The Laboratory Core will provide the assessments of soluble mediators, lymphocyte surface markers, hematological parameters and lymphocyte function in support of the scientific agenda of this Center. The following assays will be done by the Laboratory Core: Cortisol and catecholamines, norepinephrine (NE) and epinephrine (E) in urine. Testosterone, estradiol,. Estrone, sex hormone binding globulin (SHBG) and dehydroepiandrosterone-sulfate (DHEA-S) and NPY in plasma. Natural killer cell cytotoxicity (NKCC) against the tumor cell target, K562. NKCC against the tumor cell target, K562, after ex vivo exposure to interferon-gamma (IFN-gamma). Number and percent of NK (C56+CD3-), CD3+CD4+ and CD3+CD8+ lymphocytes using 4 color flow cytometry.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center (P50)
Project #
3P50CA084944-03S1
Application #
6501871
Study Section
Special Emphasis Panel (ZRG1)
Project Start
2001-09-01
Project End
2002-08-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
3
Fiscal Year
2001
Total Cost
$206,819
Indirect Cost
Name
University of Miami Coral Gables
Department
Type
DUNS #
City
Coral Gables
State
FL
Country
United States
Zip Code
33146
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Zhou, Eric S; Penedo, Frank J; Lewis, John E et al. (2010) Perceived stress mediates the effects of social support on health-related quality of life among men treated for localized prostate cancer. J Psychosom Res 69:587-90
Dodd, Stacy M; Pereira, Deidre B; Marion, Ilona et al. (2009) Depressive symptoms and cervical neoplasia in HIV+ low-income minority women with human papillomavirus infection. Int J Behav Med 16:181-8
Marion, Ilona; Antoni, Michael; Pereira, Deidre et al. (2009) Distress, sleep difficulty, and fatigue in women co-infected with HIV and HPV. Behav Sleep Med 7:180-93
Traeger, Lara; Penedo, Frank J; Gonzalez, Jeffrey S et al. (2009) Illness perceptions and emotional well-being in men treated for localized prostate cancer. J Psychosom Res 67:389-97

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