Abstract

Nature and importance of the Biostatistics Core. The Biostatistics Core will provide support for the data-management and analysis requirements of the projects and other cores of the SPORE. In addition to performing the planned analyses described in the descriptions of the individual projects, the Biostatistics Core will also assist in the design and analysis of future studies arising from the results of the proposed research and will facilitate the exchange of data and information between the various components of the SPORE. Because of the innovative nature of the research proposed and the high level of interaction between the various projects, the Biostatistics Core will play a vital role in the work of the SPORE by helping transmit results between Projects and rapidly developing new preclinical studies based on those results.
The Specific Aims of the Biostatistics Core are to: A. Provide guidance in the design and conduct of clinical trials and other experiments arising from the ongoing research of the SPORE; B. Provide the innovative statistical modeling, simulation techniques, and data analyses required by the Projects, Pilot Projects, and other Cores to achieve their Specific Aims; C. Ascertain that conclusions drawn from all Projects are based on well- designed experiments and appropriate interpretation of results.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center (P50)
Project #
5P50CA090270-02
Application #
6563954
Study Section
Special Emphasis Panel (ZCA1)
Project Start
2002-01-24
Project End
2002-12-31
Budget Start
Budget End
Support Year
2
Fiscal Year
2002
Total Cost
$291,807
Indirect Cost

  Institution

Name
University of Texas MD Anderson Cancer Center
Department
Type
DUNS #
001910777
City
Houston
State
TX
Country
United States
Zip Code
77030

  Publications

Salameh, Ahmad; Lee, Alessandro K; Cardó-Vila, Marina et al. (2015) PRUNE2 is a human prostate cancer suppressor regulated by the intronic long noncoding RNA PCA3. Proc Natl Acad Sci U S A 112:8403-8
Pasqualini, Renata; Millikan, Randall E; Christianson, Dawn R et al. (2015) Targeting the interleukin-11 receptor ? in metastatic prostate cancer: A first-in-man study. Cancer 121:2411-21
Euscher, Elizabeth; Fox, Patricia; Bassett, Roland et al. (2013) The pattern of myometrial invasion as a predictor of lymph node metastasis or extrauterine disease in low-grade endometrial carcinoma. Am J Surg Pathol 37:1728-36
Efstathiou, Eleni; Karlou, Maria; Wen, Sijin et al. (2013) Integrated Hedgehog signaling is induced following castration in human and murine prostate cancers. Prostate 73:153-61
Hosain, G M Monawar; Sanderson, Maureen; Du, Xianglin L et al. (2012) Racial/ethnic differences in treatment discussed, preferred, and received for prostate cancer in a tri-ethnic population. Am J Mens Health 6:249-57
Heymach, John V; Shackleford, Terry J; Tran, Hai T et al. (2011) Effect of low-fat diets on plasma levels of NF-?B-regulated inflammatory cytokines and angiogenic factors in men with prostate cancer. Cancer Prev Res (Phila) 4:1590-8
Hosain, G M Monawar; Sanderson, Maureen; Du, Xianglin L et al. (2011) Racial/ethnic differences in predictors of PSA screening in a tri-ethnic population. Cent Eur J Public Health 19:30-4
Kadowaki, Yoshihiko; Chari, Nikhil S; Teo, Albert E K et al. (2011) PI3 Kinase inhibition on TRAIL-induced apoptosis correlates with androgen-sensitivity and p21 expression in prostate cancer cells. Apoptosis 16:627-35
Efstathiou, Eleni; Abrahams, Neil A; Tibbs, Rita F et al. (2010) Morphologic characterization of preoperatively treated prostate cancer: toward a post-therapy histologic classification. Eur Urol 57:1030-8
Ravoori, Murali; Czaplinska, Aneta J; Sikes, Charles et al. (2010) Quantification of mineralized bone response to prostate cancer by noninvasive in vivo microCT and non-destructive ex vivo microCT and DXA in a mouse model. PLoS One 5:e9854

Showing the most recent 10 out of 153 publications