Biostatistics

Lamborn, Kathleen R.

Abstract

The Biostatistics and Clinical Core will provide support for all 5 projects as well as assisting with Developmental and Career Development projects as needed. Biostatistics, data analysis and informatics support will be provided by the Biostatistics and Clinical Core for all projects. Support will be provided for all phases of the research: experimental design, data capture,data reduction, data analysis, and reporting. Dr. Kathleen Lamborn will provide overall leadership for this component of the Core. Clinical core efforts will include physician, nursing, regulatory and data management support for proposed clinical trials that result from the translational research from SPORE research efforts. Currently clinical trials are planned in projects 3,4 and 5. Dr. Prados will provide leadership for this component.

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Specialized Center (P50)
• Project #: 5P50CA097257-08
• Application #: 7885651
• Study Section: Special Emphasis Panel (ZCA1)
• Budget Start: 2009-05-01
• Budget End: 2010-04-30
• Support Year: 8
• Fiscal Year: 2009
• Total Cost: $105,551

Institution

• Name: University of California San Francisco
• DUNS #: 094878337
• City: San Francisco
• State: CA
• Country: United States
• Zip Code: 94143

Publications

Ostrom, Quinn T; Kinnersley, Ben; Wrensch, Margaret R et al. (2018) Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21. Sci Rep 8:7352

Salas, Lucas A; Koestler, Devin C; Butler, Rondi A et al. (2018) An optimized library for reference-based deconvolution of whole-blood biospecimens assayed using the Illumina HumanMethylationEPIC BeadArray. Genome Biol 19:64

Choi, Serah; Yu, Yao; Grimmer, Matthew R et al. (2018) Temozolomide-associated hypermutation in gliomas. Neuro Oncol 20:1300-1309

Jacobs, Daniel I; Liu, Yanhong; Gabrusiewicz, Konrad et al. (2018) Germline polymorphisms in myeloid-associated genes are not associated with survival in glioma patients. J Neurooncol 136:33-39

Berntsson, Shala G; Merrell, Ryan T; Amirian, E Susan et al. (2018) Glioma-related seizures in relation to histopathological subtypes: a report from the glioma international case-control study. J Neurol 265:1432-1442

Goode, Benjamin; Joseph, Nancy M; Stevers, Meredith et al. (2018) Adenomatoid tumors of the male and female genital tract are defined by TRAF7 mutations that drive aberrant NF-kB pathway activation. Mod Pathol 31:660-673

Hayes, Josie; Yu, Yao; Jalbert, Llewellyn E et al. (2018) Genomic analysis of the origins and evolution of multicentric diffuse lower-grade gliomas. Neuro Oncol 20:632-641

Ostrom, Quinn T; Kinnersley, Ben; Armstrong, Georgina et al. (2018) Age-specific genome-wide association study in glioblastoma identifies increased proportion of 'lower grade glioma'-like features associated with younger age. Int J Cancer 143:2359-2366

Pekmezci, Melike; Stevers, Meredith; Phillips, Joanna J et al. (2018) Multinodular and vacuolating neuronal tumor of the cerebrum is a clonal neoplasm defined by genetic alterations that activate the MAP kinase signaling pathway. Acta Neuropathol 135:485-488

Behr, Spencer C; Villanueva-Meyer, Javier E; Li, Yan et al. (2018) Targeting iron metabolism in high-grade glioma with 68Ga-citrate PET/MR. JCI Insight 3: