While smoking rates have been declining within the U.S. general population for the past 4 decades, the Northern Plains tribes (which include the Oglala Sioux and other Lakota tribes) have experienced high rates of commercial tobacco use. The prevalence of smoking among these tribal groups is greater than 50% in many communities, roughly 2.5 times higher than the U.S. general population. Our primary study objective is to develop and test a culturally tailored educational intervention to encourage adoption of home smoking restrictions in Northern Plains'tribal households where children are present. We will conduct a randomized, controlled trial to test a novel biomarker feedback intervention. We will randomize 180 households to either receipt of educational materials only (control group), or receipt of educational materials plus information on urine toxin levels (e.g., cotinine and tobacco-specific nitrosamines) present in one child from the household (biomarker intervention). Cotinine is a well-recognized marker of exposure to tobacco smoke, and the intervention will provide feedback to smoking households about their children's actual exposure to environmental tobacco smoke. The primary outcome of this study will be the adoption of home smoking restrictions verified by a household air quality monitor. Our scientific aims are to: 1) Evaluate the impact of the child urinary toxin biomarker feedback intervention on the adoption of home smoking restrictions and on home air quality;2) Determine the effect of the intervention on health-related quality of life 3 and 6 months after implementation of the educational and biomarker feedback intervention;Determine the effect of the intervention on adult smokers'cigarette use, including readiness to quit, quit attempts, and cessation;4) Assess how the intervention changes cultural and social factors that relate to smoking behavior, such as traditional tobacco use and family support. We hypothesize that the intervention with child toxin biomarker feedback will increase the adoption of home smoking restrictions, beyond the effect of just receiving a brochure and education.
The findings of our project will undoubtedly be used by policymakers who will be able to more strongly and effectively champion tobacco prevention and control efforts in Native communities. In addition, our community-based participatory methods will further strengthen our tribal partner's knowledge, expertise and support for intervention research, serving to mitigate distrust of, and disillusionment by, the research process in American Indian and other underrepresented populations.
| Tanner, Julie-Anne; Henderson, Jeffrey A; Buchwald, Dedra et al. (2017) Variation in CYP2A6 and nicotine metabolism among two American Indian tribal groups differing in smoking patterns and risk for tobacco-related cancer. Pharmacogenet Genomics 27:169-178 |
| Engblom, Camilla; Pfirschke, Christina; Zilionis, Rapolas et al. (2017) Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils. Science 358: |
| Haozous, Emily A; Doorenbos, Ardith; Alvord, Lori A et al. (2016) Cancer Journey for American Indians and Alaska Natives in the Pacific Northwest?. Oncol Nurs Forum 43:625-35 |
| Hohl, Sarah D; Thompson, Beti; Krok-Schoen, Jessica L et al. (2016) Characterizing Community Health Workers on Research Teams: Results From the Centers for Population Health and Health Disparities. Am J Public Health 106:664-70 |
| Smith, Caren E; Fullerton, Stephanie M; Dookeran, Keith A et al. (2016) Using Genetic Technologies To Reduce, Rather Than Widen, Health Disparities. Health Aff (Millwood) 35:1367-73 |
| Thornton, Rachel L J; Glover, Crystal M; Cené, Crystal W et al. (2016) Evaluating Strategies For Reducing Health Disparities By Addressing The Social Determinants Of Health. Health Aff (Millwood) 35:1416-23 |
| Doorenbos, Ardith Z; Morris, Arden M; Haozous, Emily A et al. (2016) Assessing Cultural Competence Among Oncology Surgeons. J Oncol Pract 12:61-2, e14-22 |
| Sawchuk, Craig N; Van Dyke, Emily; Omidpanah, Adam et al. (2016) Barriers to Cancer Care among American Indians and Alaska Natives. J Health Care Poor Underserved 27:84-96 |
| Blacksher, Erika; Nelson, Charlene; Van Dyke, Emily et al. (2016) Conversations about Community-Based Participatory Research and Trust: ""We Are Explorers Together"". Prog Community Health Partnersh 10:305-9 |
| Morris, Arden M; Doorenbos, Ardith Z; Haozous, Emily et al. (2016) Perceptions of cancer treatment decision making among American Indians/Alaska Natives and their physicians. Psychooncology 25:1050-6 |
Showing the most recent 10 out of 25 publications
