The Lung Cancer Disparities Center will be an interdisciplinary center for research (including community based participatory research), core support and dissemination activities focused on understanding and altering the determinants of racial/ethnic and socioeconomic status (SES) disparities along the continuum of lung cancer. Cigarette smoking is the primary cause of lung cancer and the key marker of high-risk in both individuals and populations;without cigarette smoking, lung cancer would be rare. Thus, identifying effective strategies to prevent the initiation of smoking and facilitate cessation among smokers is critical to reducing the risk of lung cancer. We also need to better understand the contribution of the social environment to the onset, course, and outcomes of lung cancer. The five projects and cores have the following specific aims: 1) develop and test novel tobacco control interventions that address the social context that initiate and sustain smoking behavior;2) develop and apply sophisticated concepts, measures, and methods regarding community-focused research to all of the activities of Center;3) draw on the expertise of a multidisciplinary team of researchers to bring a social determinants perspective to the clinical factors and other individual level factors that lead to social disparities in lung cancer survival and the genetic factors that could affect the onset, course and outcomes of lung cancer;4) refine existing conceptual and methodological approaches to understanding and describing the joint contribution of race/ethnicity and SES to lung cancer;5) develop a strong and cutting-edge training program to train the population health investigators of the future;and 6) fund highly innovative and high-risk pilot projects to inform research and application concerned with jointly understanding race/ethnicity and SES to disparities in lung cancer and its determinants. Significantly, this work will be accomplished by a transdisciplinary team of researchers who have made seminal contributions to population health and health disparities, in an institutional environment in which there is substantial intellectual and financial support for such an interdisciplinary Center.

Public Health Relevance

The Center on Lung Cancer Disparities will identify how environmental conditions - related to race/ethnicity and patterns of risk produce social disparities in lung cancer outcomes by influencing multiple pathways leading to poor health. Our Center focuses on one specific condition (lung cancer) and its key behavioral determinant (cigarette smoking). Cigarette smoking is the primary cause of lung cancer and the key marker of high-risk in both individuals and populations;without cigarette smoking, lung cancer would be rare.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center (P50)
Project #
1P50CA148596-01
Application #
7867311
Study Section
Special Emphasis Panel (ZCA1-SRLB-3 (J1))
Program Officer
Srinivasan, Shobha
Project Start
2010-05-01
Project End
2015-04-30
Budget Start
2010-05-01
Budget End
2011-04-30
Support Year
1
Fiscal Year
2010
Total Cost
$1,714,436
Indirect Cost
Name
Harvard University
Department
Social Sciences
Type
Schools of Public Health
DUNS #
149617367
City
Boston
State
MA
Country
United States
Zip Code
02115
Hayashi, Hana; Tan, Andy; Kawachi, Ichiro et al. (2018) Does Segmentation Really Work? Effectiveness of Matched Graphic Health Warnings on Cigarette Packaging by Race, Gender and Chronic Disease Conditions on Cognitive Outcomes among Vulnerable Populations. J Health Commun :1-11
McCloud, Rachel Faulkenberry; Okechukwu, Cassandra; Sorensen, Glorian et al. (2017) Cigarette graphic health warning labels and information avoidance among individuals from low socioeconomic position in the U.S. Cancer Causes Control 28:351-360
Levy, Douglas E; Klinger, Elissa V; Linder, Jeffrey A et al. (2017) Cost-Effectiveness of a Health System-Based Smoking Cessation Program. Nicotine Tob Res 19:1508-1515
Ramanadhan, Shoba; Nagler, Rebekah H; McCloud, Rachel et al. (2017) Graphic health warnings as activators of social networks: A field experiment among individuals of low socioeconomic position. Soc Sci Med 175:219-227
Campbell, Joshua D; Lathan, Christopher; Sholl, Lynette et al. (2017) Comparison of Prevalence and Types of Mutations in Lung Cancers Among Black and White Populations. JAMA Oncol 3:801-809
Levy, Douglas E; Adams, Inez F; Adamkiewicz, Gary (2017) Delivering on the Promise of Smoke-Free Public Housing. Am J Public Health 107:380-383
Jackson, John W; Williams, David R; VanderWeele, Tyler J (2016) Disparities at the intersection of marginalized groups. Soc Psychiatry Psychiatr Epidemiol 51:1349-1359
Ramanadhan, Shoba; Nagler, Rebekah H; McCauley, Michael P et al. (2016) Much Ventured, Much Gained: Community-Engaged Data Collection by Adolescents and Young Adults. Prog Community Health Partnersh 10:217-24
Hohl, Sarah D; Thompson, Beti; Krok-Schoen, Jessica L et al. (2016) Characterizing Community Health Workers on Research Teams: Results From the Centers for Population Health and Health Disparities. Am J Public Health 106:664-70
Lathan, Christopher S; Cronin, Angel; Tucker-Seeley, Reginald et al. (2016) Association of Financial Strain With Symptom Burden and Quality of Life for Patients With Lung or Colorectal Cancer. J Clin Oncol 34:1732-40

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