Abstract

Administrative CoreThe administrative core of our center integrates the various elements enhancing themultidisciplinary, synergistic integration of the central theme 'Dynamics of signaling by molecularmessengers relevant to drugs of abuse.' It coordinates research enabling a focus in the areas of NIDA'smission. Because of the core, our Center is able to serve as a national resource and at Hopkins to facilitatethe integration of research activity and sharing of resources as well as providing adequate and appropriatefacilities for administrative activities. The shared facilities are located in the area of the core and funded bythe core. The Center director is part of the core enabling the individual investigators to carry out theirresponsibilities effectively. The core also enables the Center to carry out its responsibilities as regardsmentoring and career development.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Specialized Center (P50)
Project #
5P50DA000266-37
Application #
7700130
Study Section
Special Emphasis Panel (ZDA1-RXL-E (02))
Project Start
2008-06-01
Project End
2012-05-31
Budget Start
2008-06-01
Budget End
2009-05-31
Support Year
37
Fiscal Year
2008
Total Cost
$135,534
Indirect Cost

  Institution

Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218

  Publications

Hinkle, Jared T; Perepezko, Kate; Bakker, Catherine C et al. (2018) Domain-specific cognitive impairment in non-demented Parkinson's disease psychosis. Int J Geriatr Psychiatry 33:e131-e139
Hinkle, Jared T; Perepezko, Kate; Mills, Kelly A et al. (2018) Dopamine transporter availability reflects gastrointestinal dysautonomia in early Parkinson disease. Parkinsonism Relat Disord 55:8-14
Piard, Juliette; Umanah, George K Essien; Harms, Frederike L et al. (2018) A homozygous ATAD1 mutation impairs postsynaptic AMPA receptor trafficking and causes a lethal encephalopathy. Brain :
Hinkle, Jared T; Perepezko, Kate; Rosenthal, Liana S et al. (2018) Markers of impaired motor and cognitive volition in Parkinson's disease: Correlates of dopamine dysregulation syndrome, impulse control disorder, and dyskinesias. Parkinsonism Relat Disord 47:50-56
Berger, Nathan A; Besson, Valerie C; Boulares, A Hamid et al. (2018) Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases. Br J Pharmacol 175:192-222
Chern, Yijuang; Chien, Ting; Fu, Xiuping et al. (2018) Trax: A versatile signaling protein plays key roles in synaptic plasticity and DNA repair. Neurobiol Learn Mem :
Paul, Bindu D; Snyder, Solomon H (2018) Gasotransmitter hydrogen sulfide signaling in neuronal health and disease. Biochem Pharmacol 149:101-109
Vasavda, Chirag; Zaccor, Nicholas W; Scherer, Paul C et al. (2017) Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding. J Vis Exp :
Park, Alan Jung; Havekes, Robbert; Fu, Xiuping et al. (2017) Learning induces the translin/trax RNase complex to express activin receptors for persistent memory. Elife 6:
Fu, Chenglai; Xu, Jing; Cheng, Weiwei et al. (2017) Neuronal migration is mediated by inositol hexakisphosphate kinase 1 via ?-actinin and focal adhesion kinase. Proc Natl Acad Sci U S A 114:2036-2041

Showing the most recent 10 out of 108 publications