An experienced team of investigators from Cornell University's Weill Medical College and Columbia University are proposing a set of new research projects and core activities for a 10-year-old NIDA-funded MULTI-ETHNIC DRUG ABUSE PREVENTION CENTER (MDAPRC). This application has grown out of a longstanding collaborative relationship between the investigators representing the participating institutions and their recognized need for feasible and efficacious interventions designed to prevent drug abuse and reduce avoidable morbidity and mortality in multi-ethnic populations. The structure of the Center consists of two core divisions and four research projects. The functions of the adminstrative core will include administration, training, dissemination, and community liaisons. The Information Management, statistics, and Evaluation core will deal with data management and evaluation. The work of the Center is conceptualized in stages, with the focus of work during the first 10 years of funding on African-American and Hispanic-American adolescents. During the next 5-year funding period, the research of the center will focus more broadly on multi-ethnic youth with an emphasis on issues critical to enhancing the science and practice of prevention. Through a set of well-integrated studies, the proposed research will address issues related to optimizing the effectiveness of school-based prevention through an increased understanding of mediating mechanisms and factors associated with implementation fidelity, adaptation, and cost / benefits. More specifically, this research is designed to provide important new scientific knowledge concerning (1) the impact of enhanced implementation fidelity on the effectiveness of school-based prevention (Project by Botvin), (2) key factors associated with fidelity and adaptation of school-based prevention (Project by Schinke), (3) the mediating role of social / psychological factors on the etiology and prevention of drug abuse (Project by Griffin), and (4) the mediating role of physiologic factors such as pubertal development and stress reactivity on youth drug abuse (Project by Graber). In sum, the work being proposed addresses major gaps in prevention science related to the etiology and prevention of drug abuse in multi-ethnic youth and is designed to provide vitally important knowledge required for improving prevention theory and optimizing the effectiveness and sustainability of evidence-based prevention when taken to scale in real-world settings.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Specialized Center (P50)
Project #
2P50DA007656-11A1
Application #
6764977
Study Section
Special Emphasis Panel (ZDA1-RXL-E (23))
Program Officer
Sims, Belinda E
Project Start
1991-09-30
Project End
2006-08-31
Budget Start
2004-09-30
Budget End
2006-08-31
Support Year
11
Fiscal Year
2004
Total Cost
$1,384,964
Indirect Cost
Name
Weill Medical College of Cornell University
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
060217502
City
New York
State
NY
Country
United States
Zip Code
10065
Scheier, Lawrence M; Grenard, Jerry L; Holtz, Kristen D (2011) An empirical assessment of the Above the Influence advertising campaign. J Drug Educ 41:431-61
Lynne-Landsman, Sarah D; Graber, Julia A; Nichols, Tracy R et al. (2011) Is sensation seeking a stable trait or does it change over time? J Youth Adolesc 40:48-58
Nichols, Tracy R; Birnel, Sara; Graber, Julia A et al. (2010) Refusal skill ability: an examination of adolescent perceptions of effectiveness. J Prim Prev 31:127-37
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Epstein, Jennifer A; Griffin, Kenneth W; Botvin, Gilbert J (2008) A social influence model of alcohol use for inner-city adolescents: family drinking, perceived drinking norms, and perceived social benefits of drinking. J Stud Alcohol Drugs 69:397-405
Lynne, Sarah D; Graber, Julia A; Nichols, Tracy R et al. (2007) Links between pubertal timing, peer influences, and externalizing behaviors among urban students followed through middle school. J Adolesc Health 40:181.e7-13
Nichols, Tracy R; Birnbaum, Amanda S; Birnel, Sara et al. (2006) Perceived smoking environment and smoking initiation among multi-ethnic urban girls. J Adolesc Health 38:369-75
Nichols, Tracy R; Graber, Julia A; Brooks-Gunn, Jeanne et al. (2006) Ways to say no: refusal skill strategies among urban adolescents. Am J Health Behav 30:227-36
Griffin, Kenneth W; Botvin, Gilbert J; Nichols, Tracy R (2006) Effects of a school-based drug abuse prevention program for adolescents on HIV risk behavior in young adulthood. Prev Sci 7:103-12
Griffin, Kenneth W; Botvin, Gilbert J; Nichols, Tracy R (2004) Long-term follow-up effects of a school-based drug abuse prevention program on adolescent risky driving. Prev Sci 5:207-12

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