We will form a Design and Analysis Core for the University of Minnesota Transdisciplinary Tobacco Use Research Center (TTURC). The proposed Core is the same Design and Analysis Core for the TTURC of the current funding period, and is proposed to function as a part of the existing Biostatistics Core of the Cancer Center and will be directed by Dr. Le, who is Director of Biostatistics of the University of Minnesota Cancer Center. To staff this important component of the University of Minnesota TTURC, we have assembled a team of highly qualified biostatisticians. The team consists of Dr. Le and three bio-statisticians/data analysts, Dr. Fangyi Zhao, Ms. Shelby Li and Ms. Yan Zhang. Together there will be expertise in the design of pilot studies, in the design and management of laboratory studies, case-control studies, and clinical trials, in data processing, and in statistical analysis. The mission of the Design and Analysis Core is still the same mission we formed five years ago, that is to support and promote high quality transdisciplinary tobacco research as proposed in this TTURC renewal application. This core is responsible for assisting the PIs in study design, data collection and processing, quality control, data storage and retrieval, and data analysis of all studies so as to provide all investigators with a high level and broad range of expertise in data quality, management and data analysis. The key emphasis is on the quality of research.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Specialized Center (P50)
Project #
5P50DA013333-10
Application #
7631278
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
2008-06-01
Budget End
2009-05-31
Support Year
10
Fiscal Year
2008
Total Cost
$326,539
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Type
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Burns, Rachel J; Rothman, Alexander J; Fu, Steven S et al. (2016) Longitudinal Care Improves Cessation in Smokers Who Do Not Initially Respond to Treatment by Increasing Cessation Self-Efficacy, Satisfaction, and Readiness to Quit: A Mediated Moderation Analysis. Ann Behav Med 50:58-69
Konorev, Dmitri; Koopmeiners, Joseph S; Tang, Yijin et al. (2015) Measurement of the Heterocyclic Amines 2-Amino-9H-pyrido[2,3-b]indole and 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Urine: Effects of Cigarette Smoking. Chem Res Toxicol 28:2390-9
Hatsukami, Dorothy K; Donny, Eric C; Koopmeiners, Joseph S et al. (2015) Compensatory smoking from gradual and immediate reduction in cigarette nicotine content. Cancer Epidemiol Biomarkers Prev 24:472-6
Burns, Rachel J; Rothman, Alexander J; Fu, Steven S et al. (2014) The relation between social support and smoking cessation: revisiting an established measure to improve prediction. Ann Behav Med 47:369-75
Oliver, Andrew J; Jensen, Joni A; Vogel, Rachel I et al. (2013) Flavored and nonflavored smokeless tobacco products: rate, pattern of use, and effects. Nicotine Tob Res 15:88-92
Knezevich, Aleksandar; Muzic, John; Hatsukami, Dorothy K et al. (2013) Nornicotine nitrosation in saliva and its relation to endogenous synthesis of N'-nitrosonornicotine in humans. Nicotine Tob Res 15:591-5
Anderson, Kristin E; Mongin, Steven J; Sinha, Rashmi et al. (2012) Pancreatic cancer risk: associations with meat-derived carcinogen intake in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO) cohort. Mol Carcinog 51:128-37
Stepanov, Irina; Knezevich, Aleksandar; Zhang, Liqin et al. (2012) Carcinogenic tobacco-specific N-nitrosamines in US cigarettes: three decades of remarkable neglect by the tobacco industry. Tob Control 21:44-8
Hecht, Stephen S; Stepanov, Irina; Hatsukami, Dorothy K (2011) Major tobacco companies have technology to reduce carcinogen levels but do not apply it to popular smokeless tobacco products. Tob Control 20:443
Harris, Andrew C; Pentel, Paul R; Burroughs, Danielle et al. (2011) A lack of association between severity of nicotine withdrawal and individual differences in compensatory nicotine self-administration in rats. Psychopharmacology (Berl) 217:153-66

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