The Administrative Core Component 1 contains the centralized administrative functions pertaining to all 4 Scientific Components, the Biostatistics Core Component (2), the Animal Core Component (3), and the Education Core Component (4). The Administrative Core will also coordinate the scientific oversight provided by the Scientific Advisory Board, including review of Pilot Projects, and educational enrichment as provided by such activities as workshops. Administrative support will be provided for animal production (selection), genomics, statistical analyses both within and across components, educational enrichment and training, as well as setting and evaluating progress toward meeting research goals. Quality control will be an important theme guiding oversight by the Administrative Core, which includes the Executive Committee that evaluates progress towards scientific goals. Thus, the Administrative Core is structured to address two specific aims.
Specific Aim 1 : The Core provides budgetary oversight and the general coordination of all Center activities, supervised by Dr. Janowsky.
Specific Aim 2 : The Core coordinates communication among Center investigators via a secured shared drive on the University network, and the dissemination of information to outside entities, including other investigators and Centers, via the Methamphetamine Abuse Research Center (MARC) web site. Drs. Janowsky and Phillips coordinate future planning for scientific directions, with the advise of the Executive Committee and Scientific Advisory Board.
|Shabani, Shkelzen; Schmidt, Bryan; Ghimire, Bikalpa et al. (2018) Depression-like symptoms of withdrawal in a genetic mouse model of binge methamphetamine intake. Genes Brain Behav :e12533|
|Eshleman, Amy J; Nagarajan, Shanthi; Wolfrum, Katherine M et al. (2018) Structure-activity relationships of bath salt components: substituted cathinones and benzofurans at biogenic amine transporters. Psychopharmacology (Berl) :|
|McCready, Holly; Kohno, Milky; Kolessar, Michael et al. (2018) Functional MRI and delay discounting in patients infected with hepatitis C. J Neurovirol 24:738-751|
|Loftis, Jennifer M; Valerio, Juno; Taylor, Jonathan et al. (2018) S100B and Inflammatory Cytokine Levels in Blood as Potential Markers of Blood-Brain Barrier Damage and Psychiatric Impairment in Comorbid Hepatitis C Viral Infection and Alcohol Use Disorder. Alcohol Clin Exp Res :|
|Eshleman, Amy J; Wolfrum, Katherine M; Reed, John F et al. (2018) Neurochemical pharmacology of psychoactive substituted N-benzylphenethylamines: High potency agonists at 5-HT2A receptors. Biochem Pharmacol 158:27-34|
|Tosh, Dilip K; Ciancetta, Antonella; Mannes, Philip et al. (2018) Repurposing of a Nucleoside Scaffold from Adenosine Receptor Agonists to Opioid Receptor Antagonists. ACS Omega 3:12658-12678|
|McCarty, Dennis; Priest, Kelsey C; Korthuis, P Todd (2018) Treatment and Prevention of Opioid Use Disorder: Challenges and Opportunities. Annu Rev Public Health 39:525-541|
|Eastwood, Emily C; Eshleman, Amy J; Janowsky, Aaron et al. (2018) Verification of a genetic locus for methamphetamine intake and the impact of morphine. Mamm Genome 29:260-272|
|Kohno, Milky; Dennis, Laura E; McCready, Holly et al. (2018) A preliminary randomized clinical trial of naltrexone reduces striatal resting state functional connectivity in people with methamphetamine use disorder. Drug Alcohol Depend 192:186-192|
|Holton, Dwight; White, Elizabeth; McCarty, Dennis (2018) Public Health Policy Strategies to Address the Opioid Epidemic. Clin Pharmacol Ther 103:959-962|
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