Annual costs resulting from medical expenses and lost productivity due to tobacco-related disease, disability, and death, areestimated at more than $150 billion. Despite the clear economic burden of tobacco on the health care system and the availability of proven treatments for tobacco dependence, many insurance programs and health plans in the United States do not offer a comprehensive benefit for these treatments. Health insurers and health care systems seek a 'business case' for investment in cessation treatment. This study wilt contribute new data on the impacts of cessation on health care utilization and costs of smokers quitting and not quitting within a large network of primary care clinics. A unique feature of the research is the longitudinal examination of health care utilization and costs for smokers actively recruited during routine primary care visits to receive pharmacotherapy and psychosocial cessation treatment.
The specific aims of this study are to: (1) Obtain longitudinal data on health care utilization from the cohort of 1320 smokers participating in the Effectiveness study and from a sample of 633 continuing smokers identified through electronic medical record review who have not been recruited into a treatment-outcome study, (2) Using quit dates of protracted abstainers in the effectiveness study as reference points, compare health care utilization and costs among quitters and continuing smokers in the effectiveness trial cohort for two years prior to cessation and up to three and a half years post-cessation, (3) Using quit dates of protracted abstainers as reference points, compare types of health care visits and diagnoses among quitters and continuing smokers in the effectiveness study, and (4) Using data from the effectiveness study quitters (Cases) and the comparison group of patients who are continuing smokers (Controls), model the health care costs and utilization of quitters against their predicted costs had they not quit as determined from controls.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Specialized Center (P50)
Project #
5P50DA019706-10
Application #
7681550
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
2008-09-01
Budget End
2009-08-31
Support Year
10
Fiscal Year
2008
Total Cost
$463,874
Indirect Cost
Name
University of Wisconsin Madison
Department
Type
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Guerreiro, Rita; Ross, Owen A; Kun-Rodrigues, Celia et al. (2018) Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study. Lancet Neurol 17:64-74
Allen, Alicia M; Carlson, Samantha; Eberly, Lynn E et al. (2018) Use of hormonal contraceptives and smoking cessation: A preliminary report. Addict Behav 76:236-242
Deng, Sien; E McCarthy, Danielle; E Piper, Megan et al. (2018) Extreme Response Style and the Measurement of Intra-Individual Variability in Affect. Multivariate Behav Res 53:199-218
Burgess-Hull, Albert J; Roberts, Linda J; Piper, Megan E et al. (2018) The social networks of smokers attempting to quit: An empirically derived and validated classification. Psychol Addict Behav 32:64-75
Glasheen, Cristie; Johnson, Eric O; Saccone, Nancy L et al. (2018) Is the Fagerström test for nicotine dependence invariant across secular trends in smoking? A question for cross-birth cohort analysis of nicotine dependence. Drug Alcohol Depend 185:127-132
Teitelbaum, A M; Murphy, S E; Akk, G et al. (2018) Nicotine dependence is associated with functional variation in FMO3, an enzyme that metabolizes nicotine in the brain. Pharmacogenomics J 18:136-143
Hancock, D B; Guo, Y; Reginsson, G W et al. (2018) Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence. Mol Psychiatry 23:1-9
Singh, Tarjinder; Walters, James T R; Johnstone, Mandy et al. (2017) The contribution of rare variants to risk of schizophrenia in individuals with and without intellectual disability. Nat Genet 49:1167-1173
Peckham-Gregory, Erin C; Chakraborty, Rikhia; Scheurer, Michael E et al. (2017) A genome-wide association study of LCH identifies a variant in SMAD6 associated with susceptibility. Blood 130:2229-2232
Piper, Megan E; Vasilenko, Sara A; Cook, Jessica W et al. (2017) What a difference a day makes: differences in initial abstinence response during a smoking cessation attempt. Addiction 112:330-339

Showing the most recent 10 out of 120 publications