Abstract

Generalizability of effects, commonly termed transfer of training, is the gold standard for evaluating the clinical utility of rehabilitation interventions. The generalizability of rehabilitation will be assessed across all four subprojects. Pre- and post-treatment samples of relevant communication interactions between patients and family members will be recorded remotely by Outcome Core Unit staff using home-based video system technology and will be subjected to content analytic procedures. The specific objectives of the Outcome Core Unit are to assess changes in: (1) cognitive and emotional function, (2) activities of daily living (ADLs) and functional communication abilities, (3) health-related quality of life, caregiver burden and family adjustment. Specific instruments to be used include the Neurobehavioral Cognitive Status Examination and the Hamilton Rating Scale for Depression (for measurement of impairment); the ASHA Functional Assessment of Communication Skills for Adults, the Instrumental Activities of Daily Living, home assessment of target communication skills, and treatment specific functional outcome measures (for measurement of disability); the Medical Outcomes Survey, the Caregiver Strain Index, the Family Assessment Device (for measurement of handicap).

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Specialized Center (P50)
Project #
5P50DC003888-03
Application #
6593827
Study Section
Communication Disorders Review Committee (CDRC)
Project Start
2002-06-01
Project End
2003-05-31
Budget Start
Budget End
Support Year
3
Fiscal Year
2002
Total Cost
$185,017
Indirect Cost

  Institution

Name
University of Florida
Department
Type
DUNS #
073130411
City
Gainesville
State
FL
Country
United States
Zip Code
32611

  Publications

Crosson, Bruce; Moore, Anna Bacon; McGregor, Keith M et al. (2009) Regional changes in word-production laterality after a naming treatment designed to produce a rightward shift in frontal activity. Brain Lang 111:73-85
Parkinson, Bruce R; Raymer, Anastasia; Chang, Yu-Ling et al. (2009) Lesion characteristics related to treatment improvement in object and action naming for patients with chronic aphasia. Brain Lang 110:61-70
Gopinath, Kaundinya; Crosson, Bruce; McGregor, Keith et al. (2009) Selective detrending method for reducing task-correlated motion artifact during speech in event-related FMRI. Hum Brain Mapp 30:1105-19
Rothi, Leslie J Gonzalez; Fuller, Renee; Leon, Susan A et al. (2009) Errorless practice as a possible adjuvant to donepezil in Alzheimer's disease. J Int Neuropsychol Soc 15:311-22
Conway, Tim; Heilman, Kenneth M; Gopinath, Kaundinya et al. (2008) Neural substrates related to auditory working memory comparisons in dyslexia: an fMRI study. J Int Neuropsychol Soc 14:629-39
Hu, Jing; Lee, Jae-Min; Gao, Jianbo et al. (2008) Assessing a signal model and identifying brain activity from fMRI data by a detrending-based fractal analysis. Brain Struct Funct 212:417-26
Crosson, Bruce (2008) An intention manipulation to change lateralization of word production in nonfluent aphasia: current status. Semin Speech Lang 29:188-200;quiz C-4
Lee, Jae-Min; Hu, Jing; Gao, Jianbo et al. (2008) Discriminating brain activity from task-related artifacts in functional MRI: fractal scaling analysis simulation and application. Neuroimage 40:197-212
Crosson, Bruce; McGregor, Keith; Gopinath, Kaundinya S et al. (2007) Functional MRI of language in aphasia: a review of the literature and the methodological challenges. Neuropsychol Rev 17:157-77
Crosson, Bruce; Fabrizio, Katherine S; Singletary, Floris et al. (2007) Treatment of naming in nonfluent aphasia through manipulation of intention and attention: a phase 1 comparison of two novel treatments. J Int Neuropsychol Soc 13:582-94

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