Abstract

The Nephrology Radioimmunoassay Laboratory will: (1) provide investigators with analyses utilizing radioimmunoassay techniques that are necessary for the conduct of their research; (2) provide standardized procedures and quality control; (3) provide a central facility for processing and storing samples; and (4) provide a resource which will facilitate new methods that investigators deem necessary to attain the stated goals for each project. The core will be utilized by Projects 1, 2, 3, 4, 6, 7, 8 and 9.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Specialized Center (P50)
Project #
5P50DK039258-02
Application #
3918155
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
1988
Total Cost
Indirect Cost

  Institution

Name
University of Alabama Birmingham
Department
Type
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294

  Publications

Chambrey, R; Achard, J M; St John, P L et al. (1997) Evidence for an amiloride-insensitive Na+/H+ exchanger in rat renal cortical tubules. Am J Physiol 273:C1064-74
Wang, D; Balkovetz, D F; Warnock, D G (1995) Mutational analysis of transmembrane histidines in the amiloride-sensitive Na+/H+ exchanger. Am J Physiol 269:C392-402
Brown, S A; Finco, D R; Navar, L G (1995) Impaired renal autoregulatory ability in dogs with reduced renal mass. J Am Soc Nephrol 5:1768-74
Botero-Velez, M; Curtis, J J; Warnock, D G (1994) Brief report: Liddle's syndrome revisited--a disorder of sodium reabsorption in the distal tubule. N Engl J Med 330:178-81
Kudo, L H; Hawk, C T; Schafer, J A (1994) Sodium and water transport in cortical collecting duct of Dahl salt-resistant rat. Am J Physiol 267:F583-91
Lewis, J L; Warnock, D G (1994) Renal apical membrane sodium-hydrogen exchange in genetic salt-sensitive hypertension. Hypertension 24:491-8
Allon, M; Parris, M (1993) Calcitriol stimulates Na(+)-Pi cotransport in a subclone of opossum kidney cells (OK-7A) by a genomic mechanism. Am J Physiol 264:F404-10
Wuthrich, R P; Jenkins, T A; Snyder, T L (1993) Regulation of cytokine-stimulated vascular cell adhesion molecule-1 expression in renal tubular epithelial cells. Transplantation 55:172-7
Chen, P Y; St John, P L; Kirk, K A et al. (1993) Hypertensive nephrosclerosis in the Dahl/Rapp rat. Initial sites of injury and effect of dietary L-arginine supplementation. Lab Invest 68:174-84
Wuthrich, R P; Sekar, P (1993) Effect of dexamethasone, 6-mercaptopurine and cyclosporine A on intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 expression. Biochem Pharmacol 46:1349-53

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