Abstract

The mission of this Core 9001 Laboratory is to serve as a resource center for technical information on molecular biology and animal experimentation. also, the Core has the responsibility in the following areas. 1. Generation of new gene-targeted mutant mice. 2. Maintenance and supply of established mutant mice. 3. Test of the specificity of currently available synthetic angiotensin receptor antagonists.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Specialized Center (P50)
Project #
2P50DK044757-07
Application #
6270739
Study Section
Project Start
1998-07-17
Project End
1999-03-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
7
Fiscal Year
1998
Total Cost
Indirect Cost

  Institution

Name
Vanderbilt University Medical Center
Department
Type
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212

  Publications

Yamamoto, Suguru; Zhong, Jiayong; Yancey, Patricia G et al. (2015) Atherosclerosis following renal injury is ameliorated by pioglitazone and losartan via macrophage phenotype. Atherosclerosis 242:56-64
Kaseda, Ryohei; Jabs, Kathy; Hunley, Tracy E et al. (2015) Dysfunctional high-density lipoproteins in children with chronic kidney disease. Metabolism 64:263-73
Zhong, Jianyong; Yang, Hai-Chun; Kon, Valentina et al. (2014) Vitronectin-binding PAI-1 protects against the development of cardiac fibrosis through interaction with fibroblasts. Lab Invest 94:633-44
Yamamoto, Suguru; Kon, Valentina (2014) Chronic kidney disease induced dysfunction of high density lipoprotein. Clin Exp Nephrol 18:251-4
Yang, Hai-Chun; Fogo, Agnes B (2014) Mechanisms of disease reversal in focal and segmental glomerulosclerosis. Adv Chronic Kidney Dis 21:442-7
Zuo, Yiqin; Chun, Bongkwon; Potthoff, Sebastian A et al. (2013) Thymosin ?4 and its degradation product, Ac-SDKP, are novel reparative factors in renal fibrosis. Kidney Int 84:1166-75
Miyazawa, Tomoki; Zeng, Fenghua; Wang, Suwan et al. (2013) Low nitric oxide bioavailability upregulates renal heparin binding EGF-like growth factor expression. Kidney Int 84:1176-88
Yamamoto, Suguru; Yancey, Patricia G; Ikizler, T Alp et al. (2012) Dysfunctional high-density lipoprotein in patients on chronic hemodialysis. J Am Coll Cardiol 60:2372-9
Yamaguchi, Ikuyo; Tchao, Bie Nga; Burger, Megan L et al. (2012) Vascular endothelial cadherin modulates renal interstitial fibrosis. Nephron Exp Nephrol 120:e20-31
Zhong, Jianyong; Perrien, Daniel Scott; Yang, Hai-Chun et al. (2012) Maturational regression of glomeruli determines the nephron population in normal mice. Pediatr Res 72:241-8

Showing the most recent 10 out of 131 publications