Abstract

The mission of this Core 9001 Laboratory is to serve as a resource center for technical information on molecular biology and animal experimentation. also, the Core has the responsibility in the following areas. 1. Generation of new gene-targeted mutant mice. 2. Maintenance and supply of established mutant mice. 3. Test of the specificity of currently available synthetic angiotensin receptor antagonists.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Specialized Center (P50)
Project #
5P50DK044757-08
Application #
6105510
Study Section
Project Start
1999-04-01
Project End
2000-03-31
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
8
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
Vanderbilt University Medical Center
Department
Type
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212

  Publications

Kaseda, Ryohei; Jabs, Kathy; Hunley, Tracy E et al. (2015) Dysfunctional high-density lipoproteins in children with chronic kidney disease. Metabolism 64:263-73
Yamamoto, Suguru; Zhong, Jiayong; Yancey, Patricia G et al. (2015) Atherosclerosis following renal injury is ameliorated by pioglitazone and losartan via macrophage phenotype. Atherosclerosis 242:56-64
Zhong, Jianyong; Yang, Hai-Chun; Kon, Valentina et al. (2014) Vitronectin-binding PAI-1 protects against the development of cardiac fibrosis through interaction with fibroblasts. Lab Invest 94:633-44
Yamamoto, Suguru; Kon, Valentina (2014) Chronic kidney disease induced dysfunction of high density lipoprotein. Clin Exp Nephrol 18:251-4
Yang, Hai-Chun; Fogo, Agnes B (2014) Mechanisms of disease reversal in focal and segmental glomerulosclerosis. Adv Chronic Kidney Dis 21:442-7
Zuo, Yiqin; Chun, Bongkwon; Potthoff, Sebastian A et al. (2013) Thymosin ?4 and its degradation product, Ac-SDKP, are novel reparative factors in renal fibrosis. Kidney Int 84:1166-75
Miyazawa, Tomoki; Zeng, Fenghua; Wang, Suwan et al. (2013) Low nitric oxide bioavailability upregulates renal heparin binding EGF-like growth factor expression. Kidney Int 84:1176-88
Eddy, Allison A; López-Guisa, Jesús M; Okamura, Daryl M et al. (2012) Investigating mechanisms of chronic kidney disease in mouse models. Pediatr Nephrol 27:1233-47
Shimizu, Akihiro; Zhong, Jianyong; Miyazaki, Yoichi et al. (2012) ARB protects podocytes from HIV-1 nephropathy independently of podocyte AT1. Nephrol Dial Transplant 27:3169-75
Luther, James M; Luo, Pengcheng; Wang, Zuofei et al. (2012) Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury. Kidney Int 82:643-51

Showing the most recent 10 out of 131 publications