Project Start
Project End
Budget Start
Budget End
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Anwar, A; Zahid, A A; Scheidegger, K J et al. (2002) Tumor necrosis factor-alpha regulates insulin-like growth factor-1 and insulin-like growth factor binding protein-3 expression in vascular smooth muscle. Circulation 105:1220-5
Bernstein, K E; Sayeski, P P; Doan, T et al. (2001) Signal transduction pathways of angiotensin II in the kidney. Contrib Nephrol :16-33
Sayeski, P P; Ali, M S; Frank, S J et al. (2001) The angiotensin II-dependent nuclear translocation of Stat1 is mediated by the Jak2 protein motif 231YRFRR. J Biol Chem 276:10556-63
Okura, Y; Brink, M; Zahid, A A et al. (2001) Decreased expression of insulin-like growth factor-1 and apoptosis of vascular smooth muscle cells in human atherosclerotic plaque. J Mol Cell Cardiol 33:1777-89
Brink, M; Price, S R; Chrast, J et al. (2001) Angiotensin II induces skeletal muscle wasting through enhanced protein degradation and down-regulates autocrine insulin-like growth factor I. Endocrinology 142:1489-96
Keller, P F; Verin, V; Ziegler, T et al. (2001) Gamma-irradiation markedly inhibits the hydrated collagen gel contradiction by arterial smooth muscle cells. J Investig Med 49:258-64
Du, J; Brink, M; Peng, T et al. (2001) Thrombin regulates insulin-like growth factor-1 receptor transcription in vascular smooth muscle: characterization of the signaling pathway. Circ Res 88:1044-52
Sayeski, P P; Ali, M S; Bernstein, K E (2000) The role of Ca2+ mobilization and heterotrimeric G protein activation in mediating tyrosine phosphorylation signaling patterns in vascular smooth muscle cells. Mol Cell Biochem 212:91-8
Anwar, A; Zahid, A A; Phillips, L et al. (2000) Insulin-like growth factor binding protein-4 expression is decreased by angiotensin II and thrombin in rat aortic vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 20:370-6
Sayeski, P P; Ali, M S; Safavi, A et al. (1999) A catalytically active Jak2 is required for the angiotensin II-dependent activation of Fyn. J Biol Chem 274:33131-42

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