Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Specialized Center (P50)
Project #
5P50DK052620-10
Application #
7500600
Study Section
Special Emphasis Panel (ZDK1-GRB-9 (M1))
Project Start
2007-09-01
Project End
2008-08-31
Budget Start
2007-09-01
Budget End
2008-08-31
Support Year
10
Fiscal Year
2007
Total Cost
$135,216
Indirect Cost
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Hypolite, Joseph A; Chang, Shaohua; Wein, Alan J et al. (2015) Protein kinase C modulates frequency of micturition and non-voiding contractions in the urinary bladder via neuronal and myogenic mechanisms. BMC Urol 15:34
Long, C J; Butler, S; Fesi, J et al. (2014) Genetic or pharmacologic disruption of the calcineurin-nuclear factor of activated T-cells axis prevents social stress-induced voiding dysfunction in a murine model. J Pediatr Urol 10:598-604
Marx, James O; Basha, Maureen E; Mohanan, Sunish et al. (2014) Effects of Rho-kinase inhibition on myosin light chain phosphorylation and obstruction-induced detrusor overactivity. Int J Urol 21:319-24
Boopathi, Ettickan; Gomes, Cristiano; Zderic, Stephen A et al. (2014) Mechanical stretch upregulates proteins involved in Ca2+ sensitization in urinary bladder smooth muscle hypertrophy. Am J Physiol Cell Physiol 307:C542-53
Eto, Masumi; Kirkbride, Jason A; Chugh, Rishika et al. (2013) Nuclear localization of CPI-17, a protein phosphatase-1 inhibitor protein, affects histone H3 phosphorylation and corresponds to proliferation of cancer and smooth muscle cells. Biochem Biophys Res Commun 434:137-42
Hypolite, Joseph A; Lei, Qi; Chang, Shaohua et al. (2013) Spontaneous and evoked contractions are regulated by PKC-mediated signaling in detrusor smooth muscle: involvement of BK channels. Am J Physiol Renal Physiol 304:F451-62
Boopathi, Ettickan; Hypolite, Joseph A; Zderic, Stephen A et al. (2013) GATA-6 and NF-ýýB activate CPI-17 gene transcription and regulate Ca2+ sensitization of smooth muscle contraction. Mol Cell Biol 33:1085-102
Basha, Maureen E; Chang, Shaohua; Burrows, Lara J et al. (2013) Effect of estrogen on molecular and functional characteristics of the rodent vaginal muscularis. J Sex Med 10:1219-30
Wei, Wenjie; Howard, Pamela S; Macarak, Edward J (2013) Recombinant insulin-like growth factor-1 activates satellite cells in the mouse urethral rhabdosphincter. BMC Urol 13:62
Wood, Susan K; McFadden, Kile; Griffin, Tagan et al. (2013) A corticotropin-releasing factor receptor antagonist improves urodynamic dysfunction produced by social stress or partial bladder outlet obstruction in male rats. Am J Physiol Regul Integr Comp Physiol 304:R940-50

Showing the most recent 10 out of 68 publications