The University of California, San Francisco, Specialized Center of Research (UCSF SCOR) Biostatistics andData Management Core (BDMC) provides all needed data management and statistical support to the SCORnvestigators. It includes a team of experts in biostatistics, epidemiology, computer programming anddatamanagement. The majority of data management activities occur at the Kaiser Division of Research(KDOR)using sophisticated data entry systems. Statistical support comesfrom the highly productive andexperienced research team at the UCSF's Women's Health Clinical Research Center (WHCRC). Together,the BDMC is able to provide state-of-the-art science in biostatistics and data management to support thedesign, conduct, quality assurance, analysis and reporting of the multiple projects that comprise the UCSFSCOR. This includes assisting UCSF SCOR investigators with study design and planning of analyses,developing and reviewing forms for clarity, internal consistency and implications for analysis, analysesregarding the healthcare and economic burdon of incontinence, and sharing data with junior faculty at UCSFas well as faculty from other collaborating institutions. The BDMC ensures that all UCSF SCORprojectshave adequate support in statistical analysis and manuscript development. In addition, the BDMC willdevelop and maintain an informational UCSF SCOR website (www.ucsf.edu/scor) that will centralizeand monitor these tasks.The centralization of the data management and statistical components of the UCSF SCOR in the BDMCprovides efficiencies of scale, improved quality control, and cross-fertilization among multiple studies. Itfosters communication between SCOR investigators by stimulating discussion of design, analysisandinterpretive issues, and thus contributes to the interaction of basic mechanisms research and clinicalinvestigation. For the last four years, the BDMC's rigorous and timely initiation and completion of projectshas contributed to the UCSF SCOR's remarkable productivity, including 41 publications and 30 conferencepresentations. This is a testiment to the continued importance a Biostatistics and Data Management Corefor the UCSF SCOR and how it expedites the translation of research into changes in medical practice.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Specialized Center (P50)
Project #
2P50DK064538-06
Application #
7333716
Study Section
Special Emphasis Panel (ZRG1-HOP-U (40))
Project Start
Project End
Budget Start
2007-09-17
Budget End
2008-07-31
Support Year
6
Fiscal Year
2007
Total Cost
$206,587
Indirect Cost
Name
University of California San Francisco
Department
Type
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Munaganuru, Nagambika; Van Den Eeden, Stephen K; Creasman, Jennifer et al. (2017) Urine leakage during sexual activity among ethnically diverse, community-dwelling middle-aged and older women. Am J Obstet Gynecol 217:439.e1-439.e8
Duralde, Erin R; Walter, Louise C; Van Den Eeden, Stephen K et al. (2016) Bridging the gap: determinants of undiagnosed or untreated urinary incontinence in women. Am J Obstet Gynecol 214:266.e1-266.e9
Hunter, Mary M; Nakagawa, Sanae; Van Den Eeden, Stephen K et al. (2016) Predictors of impact of vaginal symptoms in postmenopausal women. Menopause 23:40-6
Hsu, Amy; Nakagawa, Sanae; Walter, Louise C et al. (2015) The burden of nocturia among middle-aged and older women. Obstet Gynecol 125:35-43
Huang, Alison J; Gregorich, Steven E; Kuppermann, Miriam et al. (2015) Day-to-Day Impact of Vaginal Aging questionnaire: a multidimensional measure of the impact of vaginal symptoms on functioning and well-being in postmenopausal women. Menopause 22:144-54
Ning, Hongxiu; Lei, Hong-En; Xu, Yong-De et al. (2014) Conversion of adipose-derived stem cells into natural killer-like cells with anti-tumor activities in nude mice. PLoS One 9:e106246
Lin, Ching-Shwun; Lue, Tom F (2013) Defining vascular stem cells. Stem Cells Dev 22:1018-26
Lin, Ching-Shwun; Albersen, Maarten; Xin, Zhongcheng et al. (2013) Phosphodiesterase-5 expression and function in the lower urinary tract: a critical review. Urology 81:480-7
Fehniger, Julia E; Brown, Jeanette S; Creasman, Jennifer M et al. (2013) Childbirth and female sexual function later in life. Obstet Gynecol 122:988-97
Lin, Ching-Shwun; Xin, Zhong-Cheng; Dai, Jican et al. (2013) Commonly used mesenchymal stem cell markers and tracking labels: Limitations and challenges. Histol Histopathol 28:1109-16

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