The Core section contains much of the 'technical glue' that binds the investigators together. This includes cell culture, wound (animal) models, oxygen and lactate measurements, service of equipment, the collagen and some of the oxygen radical assays, and other assays. Since projects two and four are highly dependent upon human wound assays, and since the future of would healing is in large measure dependent upon developing means to measure human repair, it contains some budget for continued development of human wound models. The core laboratory is also the office of the PI and contains the conference room for the majority of our meetings. It is the communications center and the site at which most of the research fellows, the UCSF-based faculty, and the research nurse have their desks, experimental spaces and computers. Sufficient up to date personal computers are available. We have a scanner, and are connected into Ethernet as well as the hospital computer network.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
5P50GM027345-19
Application #
6107485
Study Section
Project Start
1999-01-01
Project End
2000-04-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
19
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Type
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Gimbel, Michael L; Rollins, Mark D; Fukaya, Eri et al. (2009) Monitoring partial and full venous outflow compromise in a rabbit skin flap model. Plast Reconstr Surg 124:796-803
Ogino, Tetsuya; Than, Tin Aung; Hosako, Mutsumi et al. (2009) Taurine chloramine: a possible oxidant reservoir. Adv Exp Med Biol 643:451-61
Hunt, Thomas K; Aslam, Rummana S; Beckert, Stefan et al. (2007) Aerobically derived lactate stimulates revascularization and tissue repair via redox mechanisms. Antioxid Redox Signal 9:1115-24
Hansen, Scott L; Dosanjh, Amarjit; Young, David M et al. (2006) Hemangiomas and homeobox gene expression. J Craniofac Surg 17:767-71
Rosen, Noah A; Hopf, Harriet W; Hunt, Thomas K (2006) Perflubron emulsion increases subcutaneous tissue oxygen tension in rats. Wound Repair Regen 14:55-60
Hopf, Harriet W; Gibson, Jeffrey J; Angeles, Adam P et al. (2005) Hyperoxia and angiogenesis. Wound Repair Regen 13:558-64
Fries, Richard B; Wallace, William A; Roy, Sashwati et al. (2005) Dermal excisional wound healing in pigs following treatment with topically applied pure oxygen. Mutat Res 579:172-81
Hansen, Scott L; Myers, Connie A; Charboneau, Aubri et al. (2003) HoxD3 accelerates wound healing in diabetic mice. Am J Pathol 163:2421-31
Hansen, Scott L; Young, David M; Boudreau, Nancy J (2003) HoxD3 expression and collagen synthesis in diabetic fibroblasts. Wound Repair Regen 11:474-80
Trabold, Odilo; Wagner, Silvia; Wicke, Corinna et al. (2003) Lactate and oxygen constitute a fundamental regulatory mechanism in wound healing. Wound Repair Regen 11:504-9

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