Abstract

Excellent organization and communication will be the keys to our success. Both will be the responsibility of the Administrative Core. Core personnel will achieve these goals by:1) maintaining a centralized location for the accumulated grants information and research publications;2) providing efficient dissemination of information to the project and core leaders;3) arranging several key conferences and meetings which will provide oversight and planning of the research activities.

Public Health Relevance

The Administrative Core is necessary to coordinate the activities of the Center.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
5P50GM053789-16
Application #
8378357
Study Section
Special Emphasis Panel (ZGM1-PPBC-5)
Project Start
Project End
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
16
Fiscal Year
2012
Total Cost
$37,155
Indirect Cost
$12,628

  Institution

Name
University of Pittsburgh
Department
Type
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213

  Publications

Schimunek, Lukas; Namas, Rami A; Yin, Jinling et al. (2018) An Enrichment Strategy Yields Seven Novel Single Nucleotide Polymorphisms Associated With Mortality and Altered Th17 Responses Following Blunt Trauma. Shock 49:259-268
Zettel, Kent; Korff, Sebastian; Zamora, Ruben et al. (2017) Toll-Like Receptor 4 on both Myeloid Cells and Dendritic Cells Is Required for Systemic Inflammation and Organ Damage after Hemorrhagic Shock with Tissue Trauma in Mice. Front Immunol 8:1672
Sun, Qian; Loughran, Patricia; Shapiro, Richard et al. (2017) Redox-dependent regulation of hepatocyte absent in melanoma 2 inflammasome activation in sterile liver injury in mice. Hepatology 65:253-268
Zettel, Kent R; Dyer, Mitchell; Raval, Jay S et al. (2017) Aged Human Stored Red Blood Cell Supernatant Inhibits Macrophage Phagocytosis in an HMGB1 Dependent Manner After Trauma in a Murine Model. Shock 47:217-224
Moore, Frederick A; Moore, Ernest E; Billiar, Timothy R et al. (2017) The role of NIGMS P50 sponsored team science in our understanding of multiple organ failure. J Trauma Acute Care Surg 83:520-531
Yang, Jie; Zhao, Yanfeng; Zhang, Peng et al. (2016) Hemorrhagic shock primes for lung vascular endothelial cell pyroptosis: role in pulmonary inflammation following LPS. Cell Death Dis 7:e2363
Namas, Rami A; Almahmoud, Khalid; Mi, Qi et al. (2016) Individual-specific principal component analysis of circulating inflammatory mediators predicts early organ dysfunction in trauma patients. J Crit Care 36:146-153
Korff, Sebastian; Loughran, Patricia; Cai, Changchun et al. (2016) Tlr2 on Bone Marrow and Non-Bone Marrow Derived Cells Regulates Inflammation and Organ Injury in Cooperation with Tlr4 During Resuscitated Hemorrhagic Shock. Shock 46:519-526
Li, Z; Scott, M J; Fan, E K et al. (2016) Tissue damage negatively regulates LPS-induced macrophage necroptosis. Cell Death Differ 23:1428-47
Namas, Rami A; Vodovotz, Yoram; Almahmoud, Khalid et al. (2016) Temporal Patterns of Circulating Inflammation Biomarker Networks Differentiate Susceptibility to Nosocomial Infection Following Blunt Trauma in Humans. Ann Surg 263:191-8

Showing the most recent 10 out of 302 publications