Stable isotope tracers have become invaluable tools with which to investigate human metabolism. This laboratory has been involved in the application and development of stable isotope tracer methods for the past 20 years. New kinetic models and analytical approaches have been developed in this lab to investigate various aspects of glucose, fat and protein metabolism. The specific goal of this core laboratory is to make available mass spectrometry analysis for all projects involved with the Burn Center. We have all the equipment necessary to perform stable isotope enrichment measurements, including five quadrupole gas chromatograph mass spectrometers, a gas chromatography-combustion- isotope ratio mass spectrometer, an isotope ratio mass spectrometer interfaced to an elemental analyzer, and an inductively coupled plasma mass spectrometer. We also have the necessary expertise to trouble shoot and develop new analytical procedures. Our expertise in mathematical modeling will be central to the interpretation of resulting enrichment data. Training and education are also an aspect of the mass spec core activity.
| ?apek, Karel D; Culnan, Derek M; Desai, Manubhai H et al. (2018) Fifty Years of Burn Care at Shriners Hospitals for Children, Galveston. Ann Plast Surg 80:S90-S94 |
| Korkmaz-Icöz, Sevil; Szczesny, Bartosz; Marcatti, Michela et al. (2018) Olaparib protects cardiomyocytes against oxidative stress and improves graft contractility during the early phase after heart transplantation in rats. Br J Pharmacol 175:246-261 |
| Cambiaso-Daniel, Janos; Rivas, Eric; Carson, Joshua S et al. (2018) Cardiorespiratory Capacity and Strength Remain Attenuated in Children with Severe Burn Injuries at Over 3 Years Postburn. J Pediatr 192:152-158 |
| Rontoyanni, Victoria G; Malagaris, Ioannis; Herndon, David N et al. (2018) Skeletal Muscle Mitochondrial Function is Determined by Burn Severity, Sex, and Sepsis, and is Associated With Glucose Metabolism and Functional Capacity in Burned Children. Shock 50:141-148 |
| Cambiaso-Daniel, Janos; Rontoyanni, Victoria G; Foncerrada, Guillermo et al. (2018) Correlation between invasive and noninvasive blood pressure measurements in severely burned children. Burns 44:1787-1791 |
| Ojeda, Sylvia; Blumenthal, Emily; Stevens, Pamela et al. (2018) The Safety and Efficacy of Propranolol in Reducing the Hypermetabolic Response in the Pediatric Burn Population. J Burn Care Res 39:963-969 |
| Capek, Karel D; Sousse, Linda E; Hundeshagen, Gabriel et al. (2018) Contemporary Burn Survival. J Am Coll Surg 226:453-463 |
| Foncerrada, Guillermo; Culnan, Derek M; Capek, Karel D et al. (2018) Inhalation Injury in the Burned Patient. Ann Plast Surg 80:S98-S105 |
| Bohanon, Fredrick J; Nunez Lopez, Omar; Herndon, David N et al. (2018) Burn Trauma Acutely Increases the Respiratory Capacity and Function of Liver Mitochondria. Shock 49:466-473 |
| Cambiaso-Daniel, Janos; Boukovalas, Stafanos; Bitz, Genevieve H et al. (2018) Topical Antimicrobials in Burn Care: Part 1-Topical Antiseptics. Ann Plast Surg : |
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