Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
5P50GM073210-04
Application #
7478427
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2007-08-01
Budget End
2008-07-31
Support Year
4
Fiscal Year
2007
Total Cost
$182,363
Indirect Cost
Name
University of California San Francisco
Department
Type
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Metcalf, Brian; Chuang, Chihyuan; Dufu, Kobina et al. (2017) Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin. ACS Med Chem Lett 8:321-326
Dang, Bobo; Wu, Haifan; Mulligan, Vikram Khipple et al. (2017) De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures. Proc Natl Acad Sci U S A 114:10852-10857
Li, Zhe; Partridge, James; Silva-Garcia, Abel et al. (2017) Structure-Guided Design of Novel, Potent, and Selective Macrocyclic Plasma Kallikrein Inhibitors. ACS Med Chem Lett 8:185-190
Rowe, Timothy B; Luo, Zhe-Xi; Ketcham, Richard A et al. (2016) X-ray computed tomography datasets for forensic analysis of vertebrate fossils. Sci Data 3:160040
Zhou, X Edward; Gao, Xiang; Barty, Anton et al. (2016) X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex. Sci Data 3:160021
Schumacher, Maria A; Lee, Jeehyun; Zeng, Wenjie (2016) Molecular insights into DNA binding and anchoring by the Bacillus subtilis sporulation kinetochore-like RacA protein. Nucleic Acids Res 44:5438-49
Madej, M Gregor (2015) Comparative Sequence-Function Analysis of the Major Facilitator Superfamily: The ""Mix-and-Match"" Method. Methods Enzymol 557:521-49
Poncet-Montange, Guillaume; Zhan, Yanai; Bardenhagen, Jennifer P et al. (2015) Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2. Biochem J 466:337-46
Kim, JungMin; Wu, Shenping; Tomasiak, Thomas M et al. (2015) Subnanometre-resolution electron cryomicroscopy structure of a heterodimeric ABC exporter. Nature 517:396-400
Wang, Hui; Klein, Michael G; Zou, Hua et al. (2015) Crystal structure of human stearoyl-coenzyme A desaturase in complex with substrate. Nat Struct Mol Biol 22:581-5

Showing the most recent 10 out of 123 publications