Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
5P50GM073210-05
Application #
7667165
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
2008-08-01
Budget End
2009-07-31
Support Year
5
Fiscal Year
2008
Total Cost
$179,841
Indirect Cost
Name
University of California San Francisco
Department
Type
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Metcalf, Brian; Chuang, Chihyuan; Dufu, Kobina et al. (2017) Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin. ACS Med Chem Lett 8:321-326
Dang, Bobo; Wu, Haifan; Mulligan, Vikram Khipple et al. (2017) De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures. Proc Natl Acad Sci U S A 114:10852-10857
Li, Zhe; Partridge, James; Silva-Garcia, Abel et al. (2017) Structure-Guided Design of Novel, Potent, and Selective Macrocyclic Plasma Kallikrein Inhibitors. ACS Med Chem Lett 8:185-190
Zhou, X Edward; Gao, Xiang; Barty, Anton et al. (2016) X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex. Sci Data 3:160021
Schumacher, Maria A; Lee, Jeehyun; Zeng, Wenjie (2016) Molecular insights into DNA binding and anchoring by the Bacillus subtilis sporulation kinetochore-like RacA protein. Nucleic Acids Res 44:5438-49
Rowe, Timothy B; Luo, Zhe-Xi; Ketcham, Richard A et al. (2016) X-ray computed tomography datasets for forensic analysis of vertebrate fossils. Sci Data 3:160040
Kang, Yanyong; Zhou, X Edward; Gao, Xiang et al. (2015) Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser. Nature 523:561-7
Bunkóczi, Gábor; McCoy, Airlie J; Echols, Nathaniel et al. (2015) Macromolecular X-ray structure determination using weak, single-wavelength anomalous data. Nat Methods 12:127-30
Li, Dianfan; Stansfeld, Phillip J; Sansom, Mark S P et al. (2015) Ternary structure reveals mechanism of a membrane diacylglycerol kinase. Nat Commun 6:10140
Serdiuk, Tetiana; Sugihara, Junichi; Mari, Stefania A et al. (2015) Observing a lipid-dependent alteration in single lactose permeases. Structure 23:754-61

Showing the most recent 10 out of 123 publications