The Molecular Biology Core will support the CGD aims that require the use of molecular biology? techniques on a large scale. The Core will provide the following support: Project 1) prepare and track DNA? samples for resequencing and genotyping; Project by Churchill) isolate RNA from tissues, prepare and analyze? microarrays, and validate the results of the microarray experiments using quantitative real-time PCR; and? Project by Petkov) isolate DNA, followed by SNP genotyping and mapping. The procedures for Project by Churchill will be carried out in The Jackson Laboratory's Gene Expression Service (see R&E), and the genotyping for Project by Petkov will be carried out at KBiosciences (Hoddeston, Herts, UK).
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| Korstanje, Ron; Deutsch, Konstantin; Bolanos-Palmieri, Patricia et al. (2016) Loss of Kynurenine 3-Mono-oxygenase Causes Proteinuria. J Am Soc Nephrol 27:3271-3277 |
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