The continued success of a Systems Biology Center requires the continuous recruitment of new members, as well as the development of new imaging and modeling tools and expansion of our research portfolio. We foster these goals in part through a pilot project program to support innovative research that is clearly aligned with STMC goals. As described in the Administrative Core Management plan, both Full and Affiliate members of the STMC are eligible for these awards. Two pilot projects ($25,000 each) are proposed herein for year 6 of P50 funding (Year 1 of the competitive renewal period). We look forward to the successes of these talented young investigators and to promoting their career development. RFAs for future pilot projects will be announced annually on the STMC website.
This section outlines the work proposed by two young faculty, who will be awarded Pilot Projects during the first year of the competitive renewal period. In future years, RFAs for pilot projects will be announced on the STMC website and awarded after review and ranking by the STMC leadership committee.
| Tasnim, Humayra; Fricke, G Matthew; Byrum, Janie R et al. (2018) Quantitative Measurement of Naïve T Cell Association With Dendritic Cells, FRCs, and Blood Vessels in Lymph Nodes. Front Immunol 9:1571 |
| Travers, Timothy; López, Cesar A; Van, Que N et al. (2018) Molecular recognition of RAS/RAF complex at the membrane: Role of RAF cysteine-rich domain. Sci Rep 8:8461 |
| Suderman, Ryan; Mitra, Eshan D; Lin, Yen Ting et al. (2018) Generalizing Gillespie's Direct Method to Enable Network-Free Simulations. Bull Math Biol : |
| Pallikkuth, Sandeep; Martin, Cheyenne; Farzam, Farzin et al. (2018) Sequential super-resolution imaging using DNA strand displacement. PLoS One 13:e0203291 |
| López, Cesar A; Unkefer, Clifford J; Swanson, Basil I et al. (2018) Membrane perturbing properties of toxin mycolactone from Mycobacterium ulcerans. PLoS Comput Biol 14:e1005972 |
| Peretti, Amanda S; Dominguez, Dayna; Grimes, Martha M et al. (2018) The R-Enantiomer of Ketorolac Delays Mammary Tumor Development in Mouse Mammary Tumor Virus-Polyoma Middle T Antigen (MMTV-PyMT) Mice. Am J Pathol 188:515-524 |
| Brandsma, Arianne M; Schwartz, Samantha L; Wester, Michael J et al. (2018) Mechanisms of inside-out signaling of the high-affinity IgG receptor Fc?RI. Sci Signal 11: |
| Hudson, Laurie G; Gillette, Jennifer M; Kang, Huining et al. (2018) Ovarian Tumor Microenvironment Signaling: Convergence on the Rac1 GTPase. Cancers (Basel) 10: |
| Palsuledesai, Charuta C; Surviladze, Zurab; Waller, Anna et al. (2018) Activation of Rho Family GTPases by Small Molecules. ACS Chem Biol 13:1514-1524 |
| Kumar, Suresh; Jain, Ashish; Farzam, Farzin et al. (2018) Mechanism of Stx17 recruitment to autophagosomes via IRGM and mammalian Atg8 proteins. J Cell Biol 217:997-1013 |
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