CORE ABSTRACT The Administration Core will provide for the overall leadership of the University of Florida (UF) Sepsis and Critical Illness Research Center (SCIRC). It will ensure that the scientific staff remains organized and focused on shared scientific goals. It will also provide the organizational structure to help achieve the goals and objectives of the SCIRC program as a whole, as well as its individual projects and cores. It will accomplish this by directing and monitoring the UF SCIRC's day-to-day operations to ensure timely achievement of core and project milestones, in addition to promoting our investigators'new translational research initiatives. The Administration Core's main functions will be the following: -Serve as the cornerstone and support for the individual projects, cores, and participating investigators by organizing twice-weekly SOP and Adjudication meetings and twice-monthly research seminars. - Support the Steering Committee, Internal Advisory Board, External Advisory Board, and Patient Safety Monitoring Committee. - Serve as the liaison to the National Institutes of Health (NIH) and the UF Health administration, ensuring appropriate compliance, reporting, and fiscal management and promoting ongoing financial support. - Provide administrative support to the Program Director to ensure timely dissemination of information generated by this large-scale collaborative program. - Provide administrative support (accounting, ordering, travel for all investigators, research seminars) to the projects and cores and resolve conflicts that might arise out of the research program. - Serve as an advocate for SCIRC initiatives on the UF campus, including coordination with the Clinical and Translational Science Institute (CTSI), the Aging Institute, and the Departments of Surgery, Medicine, Anesthesiology, Molecular Genetics and Microbiology, Aging and Geriatric Research, and Physical Therapy. - Bring internationally known scientists to UF Health by organizing an annual visiting professorship, semi- annual streamed videoconferences with the External Advisory Board, and a biannual

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Specialized Center (P50)
Project #
1P50GM111152-01
Application #
8740714
Study Section
Special Emphasis Panel (ZGM1-PPBC-5 (TB))
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
1
Fiscal Year
2014
Total Cost
$226,968
Indirect Cost
$75,656
Name
University of Florida
Department
Type
DUNS #
969663814
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Loftus, Tyler J; Morrow, Megan L; Lottenberg, Lawrence et al. (2018) The Impact of Prior Laparotomy and Intra-abdominal Adhesions on Bowel and Mesenteric Injury Following Blunt Abdominal Trauma. World J Surg :
Loftus, Tyler J; Mira, Juan C; Miller, Elizabeth S et al. (2018) The Postinjury Inflammatory State and the Bone Marrow Response to Anemia. Am J Respir Crit Care Med 198:629-638
Loftus, Tyler J; Kannan, Kolenkode B; Carter, Christy S et al. (2018) Persistent injury-associated anemia and aging: Novel insights. J Trauma Acute Care Surg 84:490-496
Loftus, Tyler J; Dessaigne, Camille G; Croft, Chasen A et al. (2018) A protocol for non-operative management of uncomplicated appendicitis. J Trauma Acute Care Surg 84:358-364
Rincon, J C; Cuenca, A L; Raymond, S L et al. (2018) Adjuvant pretreatment with alum protects neonatal mice in sepsis through myeloid cell activation. Clin Exp Immunol 191:268-278
Brakenridge, Scott C; Efron, Philip A; Stortz, Julie A et al. (2018) The impact of age on the innate immune response and outcomes after severe sepsis/septic shock in trauma and surgical intensive care unit patients. J Trauma Acute Care Surg 85:247-255
Loftus, Tyler J; Morrow, Megan L; Lottenberg, Lawrence et al. (2018) Occult bowel injury after blunt abdominal trauma. Am J Surg :
Kilar, Cody R; Diao, YanPeng; Sautina, Larysa et al. (2018) Activation of the ?-common receptor by erythropoietin impairs acetylcholine-mediated vasodilation in mouse mesenteric arterioles. Physiol Rep 6:e13751
Loftus, Tyler J; Efron, Philip A; Bala, Trina M et al. (2018) Hypertonic saline resuscitation after emergent laparotomy and temporary abdominal closure. J Trauma Acute Care Surg 84:350-357
Stortz, Julie A; Murphy, Tyler J; Raymond, Steven L et al. (2018) Evidence for Persistent Immune Suppression in Patients Who Develop Chronic Critical Illness After Sepsis. Shock 49:249-258

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