Abstract

The experiments carried out under the plans for the Specialized Population Research Centers grant are concerned with the biochemistry of steroid and polypeptide hormones, the investigation of ovarian and adreno-cortical steroid pathways, primate neuroendocrine control of reproduction, and biochemical and genetical aspects of infertile human males.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Specialized Center (P50)
Project #
5P50HD005077-17
Application #
3106112
Study Section
Population Research and Training Committee (HDPR)
Project Start
1975-04-30
Project End
1989-03-31
Budget Start
1987-04-01
Budget End
1988-03-31
Support Year
17
Fiscal Year
1987
Total Cost
Indirect Cost

  Institution

Name
Columbia University (N.Y.)
Department
Type
Schools of Medicine
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10027

  Publications

Zhang, Q; Ahuja, H S; Zakeri, Z F et al. (1997) Cyclin-dependent kinase 5 is associated with apoptotic cell death during development and tissue remodeling. Dev Biol 183:222-33
Rhee, K; Wolgemuth, D J (1997) The NIMA-related kinase 2, Nek2, is expressed in specific stages of the meiotic cell cycle and associates with meiotic chromosomes. Development 124:2167-77
Ravnik, S E; Wolgemuth, D J (1996) The developmentally restricted pattern of expression in the male germ line of a murine cyclin A, cyclin A2, suggests roles in both mitotic and meiotic cell cycles. Dev Biol 173:69-78
Wu, S; Wolgemuth, D J (1995) The distinct and developmentally regulated patterns of expression of members of the mouse Cdc25 gene family suggest differential functions during gametogenesis. Dev Biol 170:195-206
Ravnik, S E; Rhee, K; Wolgemuth, D J (1995) Distinct patterns of expression of the D-type cyclins during testicular development in the mouse. Dev Genet 16:171-8
Rhee, K; Wolgemuth, D J (1995) Cdk family genes are expressed not only in dividing but also in terminally differentiated mouse germ cells, suggesting their possible function during both cell division and differentiation. Dev Dyn 204:406-20
Winer, M A; Wolgemuth, D J (1995) The segment-specific pattern of A-raf expression in the mouse epididymis is regulated by testicular factors. Endocrinology 136:2561-72
Mehta, N D; Don, J; Zinn, S A et al. (1994) Proenkephalin gene expression in testicular interstitial cells is down-regulated coincident with the appearance of pachytene spermatocytes. Endocrinology 135:1543-50
Don, J; Winer, M A; Wolgemuth, D J (1994) Developmentally regulated expression during gametogenesis of the murine gene meg1 suggests a role in meiosis. Mol Reprod Dev 38:16-23
Chapman, D L; Wolgemuth, D J (1994) Regulation of M-phase promoting factor activity during development of mouse male germ cells. Dev Biol 165:500-6

Showing the most recent 10 out of 30 publications