The Measurement and Imaging Core will assist with measurements of perineal geometry during the late second stage of labor in 50 women, and of pelvic floor load-displacement behavior in 32 women using a posterior weighted speculum at the time of pelvic surgery. The Core will assist with clinical measurements and standardized data sets from magnetic resonance (MR) imaging to be made on the 175 and 150 women completing Projects 2 and 3, respectively. In Projects 2 &3, subject-specific pelvic floor model geometries will be developed from reconstructing the magnetic resonance (MR) images. Additionally, in Project 2 the post natal recovery of normal MR signal intensity will be tracked over time in the pubovisceral muscles. In Project 3, MR measurements of posterior vaginal wall geometry will be made. Lastly, the Core will provide bioengineering and technical support to each project. For Projects 2 &3 it will provide technical support for all urethral pressure measurements (MUCPR and MUCPMvc) to be made using 8F catheter, maintain the hardware and software of the instrumented speculum used to measure levator ani contractile properties (LAR and I_AMVC,), and analyze and provide cleaned data sets to Core A for statistical analysis.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Specialized Center (P50)
Project #
5P50HD044406-08
Application #
7929919
Study Section
Special Emphasis Panel (ZRG1)
Project Start
Project End
Budget Start
2009-09-01
Budget End
2010-08-31
Support Year
8
Fiscal Year
2009
Total Cost
$228,800
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
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