The central goal of this project is to understand how ADHD influences processing speed, working memory,and reading comprehension in fourth- through eighth-graders. In the upper-elementary grades and beyond,students are expected to independently read (and learn from) longer and more challenging texts than atyounger ages, and children with ADHD increasingly exhibit deficiencies in text comprehension even if theaccuracy of their word recognition skills is unimpaired. Although past research has consistently foundassociations between reading disabilities (RD) and ADHD, most RD samples have included mainly childrenwith word reading deficits (WRD) or reading disorders defined by a broad composite score (word readingaccuracy and comprehension combined). In the proposed work, we instead focus on students with specificdeficits in reading comprehension alone, and investigate their speed of processing and working memory(both important components of executive function), in comparison to typically developing readers. Deficits inthese two areas are expected to elucidate the impact of ADHD upon reading comprehension, but potentiallythrough different mechanisms. Further, the use of both behavioral and neurobiological (ERP, fMRI)measures in this research will permit brain-behavior relationships pertaining to these two areas to beexamined. Specifically, the aims of the project are (1) to determine the behavioral and neurobiologicalcomponents of processing speed, the impact of ADHD, and their contribution to reading fluency; (2) todetermine the behavioral and neurobiological correlates of working memory, the impact of ADHD, and theircontribution to reading comprehension; and (3) to determine the differential effects of repeated exposure andpractice on automaticity and reading fluency in children with ADHD. ERP methods will be employed in Aim 1to address 'response preparation' within processing speed. fMRI methods will be employed in Aim 2 todiscriminate between two memory components: short term (phonological loop/maintenance) and working(central executive/manipulation).

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Specialized Center (P50)
Project #
5P50HD052121-03
Application #
7699910
Study Section
Special Emphasis Panel (ZHD1-DSR-H (27))
Project Start
2008-08-01
Project End
2011-07-31
Budget Start
2008-08-01
Budget End
2009-07-31
Support Year
3
Fiscal Year
2008
Total Cost
$58,313
Indirect Cost
Name
Hugo W. Moser Research Institute Kennedy Krieger
Department
Type
DUNS #
155342439
City
Baltimore
State
MD
Country
United States
Zip Code
21205
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