Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Specialized Center (P50)
Project #
5P50HL042384-04
Application #
3106865
Study Section
Special Emphasis Panel (SRC (TE))
Project Start
1988-09-30
Project End
1993-09-29
Budget Start
1991-09-30
Budget End
1992-09-29
Support Year
4
Fiscal Year
1991
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Coakley, Raymond D; Grubb, Barbara R; Paradiso, Anthony M et al. (2003) Abnormal surface liquid pH regulation by cultured cystic fibrosis bronchial epithelium. Proc Natl Acad Sci U S A 100:16083-8
Tarran, R; Grubb, B R; Gatzy, J T et al. (2001) The relative roles of passive surface forces and active ion transport in the modulation of airway surface liquid volume and composition. J Gen Physiol 118:223-36
Tarran, R; Grubb, B R; Parsons, D et al. (2001) The CF salt controversy: in vivo observations and therapeutic approaches. Mol Cell 8:149-58
Paradiso, A M; Ribeiro, C M; Boucher, R C (2001) Polarized signaling via purinoceptors in normal and cystic fibrosis airway epithelia. J Gen Physiol 117:53-67
Huang, P; Trotter, K; Boucher, R C et al. (2000) PKA holoenzyme is functionally coupled to CFTR by AKAPs. Am J Physiol Cell Physiol 278:C417-22
Matsui, H; Davis, C W; Tarran, R et al. (2000) Osmotic water permeabilities of cultured, well-differentiated normal and cystic fibrosis airway epithelia. J Clin Invest 105:1419-27
Bartlett, J S; Kleinschmidt, J; Boucher, R C et al. (1999) Targeted adeno-associated virus vector transduction of nonpermissive cells mediated by a bispecific F(ab'gamma)2 antibody. Nat Biotechnol 17:181-6
Grubb, B R (1999) Ion transport across the normal and CF neonatal murine intestine. Am J Physiol 277:G167-74
Noone, P G; Bennett, W D; Regnis, J A et al. (1999) Effect of aerosolized uridine-5'-triphosphate on airway clearance with cough in patients with primary ciliary dyskinesia. Am J Respir Crit Care Med 160:144-9
Paradiso, A M; Brown, H A; Ye, H et al. (1999) Heterogeneous responses of cell Ca2+ in human airway epithelium. Exp Lung Res 25:277-90

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