Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Specialized Center (P50)
Project #
5P50HL042385-09
Application #
2028452
Study Section
Special Emphasis Panel (ZHL1-CSR-B (M2))
Project Start
1988-09-30
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Iowa
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Graham, Scott M; Scott, Shaun N; Launspach, Janice et al. (2002) The effects of fluticasone propionate on nasal epithelial potential difference. Am J Rhinol 16:145-9
Welsh, Michael J; Price, Margaret P; Xie, Jinghui (2002) Biochemical basis of touch perception: mechanosensory function of degenerin/epithelial Na+ channels. J Biol Chem 277:2369-72
Ostedgaard, L S; Baldursson, O; Welsh, M J (2001) Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by its R domain. J Biol Chem 276:7689-92
Sawai, M V; Jia, H P; Liu, L et al. (2001) The NMR structure of human beta-defensin-2 reveals a novel alpha-helical segment. Biochemistry 40:3810-6
Prince, L S; Karp, P H; Moninger, T O et al. (2001) KGF alters gene expression in human airway epithelia: potential regulation of the inflammatory response. Physiol Genomics 6:81-9
Zabner, J; Seiler, M P; Launspach, J L et al. (2000) The osmolyte xylitol reduces the salt concentration of airway surface liquid and may enhance bacterial killing. Proc Natl Acad Sci U S A 97:11614-9
Jepsen, M; Graham, S; Karp, P H et al. (2000) Effect of topical nasal pharmaceuticals on sodium and chloride transport by human airway epithelia. Am J Rhinol 14:405-9
Ostedgaard, L S; Zeiher, B; Welsh, M J (1999) Processing of CFTR bearing the P574H mutation differs from wild-type and deltaF508-CFTR. J Cell Sci 112 ( Pt 13):2091-8
Cotten, J F; Welsh, M J (1999) Cystic fibrosis-associated mutations at arginine 347 alter the pore architecture of CFTR. Evidence for disruption of a salt bridge. J Biol Chem 274:5429-35
McCray Jr, P B; Zabner, J; Jia, H P et al. (1999) Efficient killing of inhaled bacteria in DeltaF508 mice: role of airway surface liquid composition. Am J Physiol 277:L183-90

Showing the most recent 10 out of 61 publications