Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Specialized Center (P50)
Project #
5P50HL046481-05
Application #
2346524
Study Section
Project Start
Project End
Budget Start
1995-10-01
Budget End
1996-09-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Colorado Denver
Department
Type
DUNS #
065391526
City
Aurora
State
CO
Country
United States
Zip Code
80045
Ivy, D Dunbar; Lee, Dong-Seok; Rairigh, Robyn L et al. (2004) Endothelin B receptor blockade attenuates pulmonary vasodilation in oxygen-ventilated fetal lambs. Biol Neonate 86:155-9
Grover, Theresa R; Parker, Thomas A; Zenge, Jeanne P et al. (2003) Intrauterine hypertension decreases lung VEGF expression and VEGF inhibition causes pulmonary hypertension in the ovine fetus. Am J Physiol Lung Cell Mol Physiol 284:L508-17
Grover, Theresa R; Zenge, Jeanne P; Parker, Thomas A et al. (2002) Vascular endothelial growth factor causes pulmonary vasodilation through activation of the phosphatidylinositol-3-kinase-nitric oxide pathway in the late-gestation ovine fetus. Pediatr Res 52:907-12
Storme, Laurent; Parker, Thomas A; Kinsella, John P et al. (2002) Chronic hypertension impairs flow-induced vasodilation and augments the myogenic response in fetal lung. Am J Physiol Lung Cell Mol Physiol 282:L56-66
Rairigh, R L; Parker, T A; Ivy, D D et al. (2001) Role of inducible nitric oxide synthase in the pulmonary vascular response to birth-related stimuli in the ovine fetus. Circ Res 88:721-6
Parker, T A; Afshar, S; Kinsella, J P et al. (2001) Effects of chronic estrogen-receptor blockade on ovine perinatal pulmonary circulation. Am J Physiol Heart Circ Physiol 281:H1005-14
Parker, T A; le Cras, T D; Kinsella, J P et al. (2000) Developmental changes in endothelial nitric oxide synthase expression and activity in ovine fetal lung. Am J Physiol Lung Cell Mol Physiol 278:L202-8
Cornfield, D N; Resnik, E R; Herron, J M et al. (2000) Chronic intrauterine pulmonary hypertension decreases calcium-sensitive potassium channel mRNA expression. Am J Physiol Lung Cell Mol Physiol 279:L857-62
Parker, T A; Kinsella, J P; Galan, H L et al. (2000) Prolonged infusions of estradiol dilate the ovine fetal pulmonary circulation. Pediatr Res 47:89-96
Parker, T A; Ivy, D D; Galan, H L et al. (2000) Estradiol improves pulmonary hemodynamics and vascular remodeling in perinatal pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 278:L374-81

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