Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Specialized Center (P50)
Project #
5P50HL050160-04
Application #
2028901
Study Section
Special Emphasis Panel (ZHL1-CSR-B (M2))
Project Start
1993-09-30
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Liedtke, C M; Cody, D; Cole, T S (2001) Differential regulation of Cl- transport proteins by PKC in Calu-3 cells. Am J Physiol Lung Cell Mol Physiol 280:L739-47
Liedtke, C M; Cole, T S (2000) PKC signaling in CF/T43 cell line: regulation of NKCC1 by PKC-delta isotype. Biochim Biophys Acta 1495:24-33
Steagall, W K; Drumm, M L (1999) Stimulation of cystic fibrosis transmembrane conductance regulator-dependent short-circuit currents across DeltaF508 murine intestines. Gastroenterology 116:1379-88
Nanduri, J; Mitra, S; Andrei, C et al. (1999) An unexpected link between the secretory path and the organization of the nucleus. J Biol Chem 274:33785-9
Kelley, T J; Cotton, C U; Drumm, M L (1998) Regulation of amiloride-sensitive sodium absorption in murine airway epithelium by C-type natriuretic peptide. Am J Physiol 274:L990-6
Kelley, T J; Drumm, M L (1998) Inducible nitric oxide synthase expression is reduced in cystic fibrosis murine and human airway epithelial cells. J Clin Invest 102:1200-7
Steagall, W K; Kelley, T J; Marsick, R J et al. (1998) Type II protein kinase A regulates CFTR in airway, pancreatic, and intestinal cells. Am J Physiol 274:C819-26
Liedtke, C M; Cole, T S (1998) Antisense oligonucleotide to PKC-epsilon alters cAMP-dependent stimulation of CFTR in Calu-3 cells. Am J Physiol 275:C1357-64
Liedtke, C M; Cole, T (1997) Antisense oligodeoxynucleotide to PKC-delta blocks alpha 1-adrenergic activation of Na-K-2Cl cotransport. Am J Physiol 273:C1632-40
Kelley, T J; Thomas, K; Milgram, L J et al. (1997) In vivo activation of the cystic fibrosis transmembrane conductance regulator mutant deltaF508 in murine nasal epithelium. Proc Natl Acad Sci U S A 94:2604-8

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