Abstract

The Administrative Core will be responsible for the coordination of the SCOR grant including integration of the separate Projects and the financial management of the grant. The unique responsibilities of the Administrative Core include support for the Internal and External Scientific Advisory Boards including yearly evaluations of the SCOR projects and the bin-annually evaluation of the new investigators Pilot Project applications, accurate record keeping, and required reports to years at $50,000/year. The purpose of the Pilot Project funding is to support promising junior investigators until their receive their first NIH funding as Principal Investigators.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Specialized Center (P50)
Project #
5P50HL054850-08
Application #
6663402
Study Section
Special Emphasis Panel (ZHL1)
Project Start
2002-09-01
Project End
2003-08-31
Budget Start
Budget End
Support Year
8
Fiscal Year
2002
Total Cost
$185,521
Indirect Cost

  Institution

Name
Children's Hospital of Los Angeles
Department
Type
DUNS #
094878337
City
Los Angeles
State
CA
Country
United States
Zip Code
90027

  Publications

Candotti, Fabio; Shaw, Kit L; Muul, Linda et al. (2012) Gene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans. Blood 120:3635-46
Rappeport, Joel M; O'Reilly, Richard J; Kapoor, Neena et al. (2010) Hematopoietic stem cell transplantation for severe combined immune deficiency or what the children have taught us. Immunol Allergy Clin North Am 30:17-30
Bauer, Gerhard; Dao, Mo A; Case, Scott S et al. (2008) In vivo biosafety model to assess the risk of adverse events from retroviral and lentiviral vectors. Mol Ther 16:1308-15
Dao, Mo A; Nolta, Jan A (2007) Cytokine and integrin stimulation synergize to promote higher levels of GATA-2, c-myb, and CD34 protein in primary human hematopoietic progenitors from bone marrow. Blood 109:2373-9
Engel, Barbara C; Podsakoff, Greg M; Ireland, Joanna L et al. (2007) Prolonged pancytopenia in a gene therapy patient with ADA-deficient SCID and trisomy 8 mosaicism: a case report. Blood 109:503-6
Hollis, Roger P; Nightingale, Sarah J; Wang, Xiuli et al. (2006) Stable gene transfer to human CD34(+) hematopoietic cells using the Sleeping Beauty transposon. Exp Hematol 34:1333-43
Hess, David A; Wirthlin, Louisa; Craft, Timothy P et al. (2006) Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells. Blood 107:2162-9
Montecino-Rodriguez, Encarnacion; Leathers, Hyosuk; Dorshkind, Kenneth (2006) Identification of a B-1 B cell-specified progenitor. Nat Immunol 7:293-301
Buckley, S; Barsky, L; Weinberg, K et al. (2005) In vivo inosine protects alveolar epithelial type 2 cells against hyperoxia-induced DNA damage through MAP kinase signaling. Am J Physiol Lung Cell Mol Physiol 288:L569-75
Podsakoff, Greg M; Engel, Barbara C; Carbonaro, Denise A et al. (2005) Selective survival of peripheral blood lymphocytes in children with HIV-1 following delivery of an anti-HIV gene to bone marrow CD34(+) cells. Mol Ther 12:77-86

Showing the most recent 10 out of 55 publications