Abstract

The function of this core is to provide histopathological, immunohistochemical, in situ hybridization, ultrastructural morphologic, and quantitative morphological support to the research projects from a central core facility. This facility provides an environment where studies are performed in a uniform manner allowing for better quality control. This leads to an overall conservation of resources by avoiding redundancy of supplies and equipment in the individual projects. The interaction of the morphology core personnel with each investigator will also facilitate communication regarding the development of techniques and regarding each project's morphological findings. This will lead to increased efficiency and conservation of monies in each project.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Specialized Center (P50)
Project #
5P50HL056556-02
Application #
6273205
Study Section
Project Start
1997-12-01
Project End
1998-11-30
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
2
Fiscal Year
1998
Total Cost
Indirect Cost

  Institution

Name
National Jewish Health
Department
Type
DUNS #
City
Denver
State
CO
Country
United States
Zip Code
80206

  Publications

Fujita, Masaki; Shannon, John M; Ouchi, Hiroshi et al. (2005) Serum surfactant protein D is increased in acute and chronic inflammation in mice. Cytokine 31:25-33
Fujita, Masaki; Shannon, John M; Morikawa, Osamu et al. (2003) Overexpression of tumor necrosis factor-alpha diminishes pulmonary fibrosis induced by bleomycin or transforming growth factor-beta. Am J Respir Cell Mol Biol 29:669-76
Mason, Robert J; Pan, Tianli; Edeen, Karen E et al. (2003) Keratinocyte growth factor and the transcription factors C/EBP alpha, C/EBP delta, and SREBP-1c regulate fatty acid synthesis in alveolar type II cells. J Clin Invest 112:244-55
Wynes, Murry W; Riches, David W H (2003) Induction of macrophage insulin-like growth factor-I expression by the Th2 cytokines IL-4 and IL-13. J Immunol 171:3550-9
Cottin, Vincent; Doan, Joyce E S; Riches, David W H (2002) Restricted localization of the TNF receptor CD120a to lipid rafts: a novel role for the death domain. J Immunol 168:4095-102
Greene, K E; King Jr, T E; Kuroki, Y et al. (2002) Serum surfactant proteins-A and -D as biomarkers in idiopathic pulmonary fibrosis. Eur Respir J 19:439-46
Fehrenbach, H; Fehrenbach, A; Pan, T et al. (2002) Keratinocyte growth factor-induced proliferation of rat airway epithelium is restricted to Clara cells in vivo. Eur Respir J 20:1185-97
Mason, Robert J; Lewis, Michele C; Edeen, Karen E et al. (2002) Maintenance of surfactant protein A and D secretion by rat alveolar type II cells in vitro. Am J Physiol Lung Cell Mol Physiol 282:L249-58
Fujita, Masaki; Mason, Robert J; Cool, Carleyne et al. (2002) Pulmonary hypertension in TNF-alpha-overexpressing mice is associated with decreased VEGF gene expression. J Appl Physiol 93:2162-70
Pan, Tianli; Nielsen, Larry D; Allen, Martin J et al. (2002) Serum SP-D is a marker of lung injury in rats. Am J Physiol Lung Cell Mol Physiol 282:L824-32

Showing the most recent 10 out of 38 publications