Abstract

The cell culture Core laboratory will serve as a cell culture resource for the investigators in the SCOR. It will maintain various types of endothelial cells and transformed cell lines. In addition the laboratory will prepare an artificial endothelial cell culture system using capillary modules. It will utilize facilities for the Institute of Environmental Medicine Cell Culture Core and contains all equipment necessary for cell maintenance and propagation including incubators, laminar flow hoods, inverted microscopes, a sterile room, and an autoclave. The personnel will include the Director, Dr. Sandra Bates, who has extensive experience in cell culture and Kristine Debolt, the tissue culture technician.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Specialized Center (P50)
Project #
5P50HL060290-04
Application #
6481634
Study Section
Project Start
2001-09-01
Project End
2002-08-31
Budget Start
Budget End
Support Year
4
Fiscal Year
2001
Total Cost
Indirect Cost

  Institution

Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104

  Publications

Ferguson, Jane F; Meyer, Nuala J; Qu, Liming et al. (2015) Integrative genomics identifies 7p11.2 as a novel locus for fever and clinical stress response in humans. Hum Mol Genet 24:1801-12
Reilly, John P; Meyer, Nuala J; Shashaty, Michael G S et al. (2014) ABO blood type A is associated with increased risk of ARDS in whites following both major trauma and severe sepsis. Chest 145:753-761
Chatterjee, Shampa; Nieman, Gary F; Christie, Jason D et al. (2014) Shear stress-related mechanosignaling with lung ischemia: lessons from basic research can inform lung transplantation. Am J Physiol Lung Cell Mol Physiol 307:L668-80
Reilly, John P; Bellamy, Scarlett; Shashaty, Michael G S et al. (2014) Heterogeneous phenotypes of acute respiratory distress syndrome after major trauma. Ann Am Thorac Soc 11:728-36
Shashaty, Michael G S; Kalkan, Esra; Bellamy, Scarlett L et al. (2014) Computed tomography-defined abdominal adiposity is associated with acute kidney injury in critically ill trauma patients*. Crit Care Med 42:1619-28
Meyer, Nuala J; Feng, Rui; Li, Mingyao et al. (2013) IL1RN coding variant is associated with lower risk of acute respiratory distress syndrome and increased plasma IL-1 receptor antagonist. Am J Respir Crit Care Med 187:950-9
Meyer, Nuala J; Daye, Zhongyin John; Rushefski, Melanie et al. (2012) SNP-set analysis replicates acute lung injury genetic risk factors. BMC Med Genet 13:52
Tejera, Paula; Meyer, Nuala J; Chen, Feng et al. (2012) Distinct and replicable genetic risk factors for acute respiratory distress syndrome of pulmonary or extrapulmonary origin. J Med Genet 49:671-80
Shashaty, Michael G S; Meyer, Nuala J; Localio, A Russell et al. (2012) African American race, obesity, and blood product transfusion are risk factors for acute kidney injury in critically ill trauma patients. J Crit Care 27:496-504
Christie, Jason D; Wurfel, Mark M; Feng, Rui et al. (2012) Genome wide association identifies PPFIA1 as a candidate gene for acute lung injury risk following major trauma. PLoS One 7:e28268

Showing the most recent 10 out of 61 publications