Core C, Clinical Research Skills Development Core, is a training core with the Specific Aim of developing translational investigators in acute lung injury and related research areas. The philosophy behind our training plan is that a translational investigator will have a primary research discipline, either in basic research or clinical outcomes research, and will enhance this with cross-training (but not equal training) in the other discipline. Our assumption is that these investigators will work with others in collaborative translational research and that their cross-training as a translational researcher will stimulate both a higher quality and a greater quantity of translational investigations. Our program already has strong training programs for basic research and clinical outcomes research training in place. In this Core C proposal we describe additional training elements to be developed and how they will be blended with current training elements to form a comprehensive program allowing appropriate training of the translational investigator. It is our hypothesis that this training will improve the translation of basic research advances into clinical benefits for patients with acute lung injury.
Morrell, Eric D; O'Mahony, D Shane; Glavan, Bradford J et al. (2018) Genetic Variation in MAP3K1 Associates with Ventilator-Free Days in Acute Respiratory Distress Syndrome. Am J Respir Cell Mol Biol 58:117-125 |
Morrell, Eric D; Radella 2nd, Frank; Manicone, Anne M et al. (2018) Peripheral and Alveolar Cell Transcriptional Programs Are Distinct in Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med 197:528-532 |
Esposito, Anthony J; Bhatraju, Pavan K; Stapleton, Renee D et al. (2017) Hyaluronic acid is associated with organ dysfunction in acute respiratory distress syndrome. Crit Care 21:304 |
Mikacenic, Carmen; Price, Brenda L; Harju-Baker, Susanna et al. (2017) A Two-Biomarker Model Predicts Mortality in the Critically Ill with Sepsis. Am J Respir Crit Care Med 196:1004-1011 |
Skerrett, Shawn J; Braff, Marissa H; Liggitt, H Denny et al. (2017) Toll-like receptor 2 has a prominent but nonessential role in innate immunity toStaphylococcus aureuspneumonia. Physiol Rep 5: |
Gharib, Sina A; Mar, Daniel; Bomsztyk, Karol et al. (2016) SYSTEM-WIDE MAPPING OF ACTIVATED CIRCUITRY IN EXPERIMENTAL SYSTEMIC INFLAMMATORY RESPONSE SYNDROME. Shock 45:148-56 |
Mikacenic, Carmen; Hansen, Elizabeth E; Radella, Frank et al. (2016) Interleukin-17A Is Associated With Alveolar Inflammation and Poor Outcomes in Acute Respiratory Distress Syndrome. Crit Care Med 44:496-502 |
Altemeier, William A; Liles, W Conrad; Villagra-Garcia, Ana et al. (2013) Ischemia-reperfusion lung injury is attenuated in MyD88-deficient mice. PLoS One 8:e77123 |
Bejan, Cosmin A; Vanderwende, Lucy; Wurfel, Mark M et al. (2012) Assessing pneumonia identification from time-ordered narrative reports. AMIA Annu Symp Proc 2012:1119-28 |
Chaffin, Donald O; Taylor, Destry; Skerrett, Shawn J et al. (2012) Changes in the Staphylococcus aureus transcriptome during early adaptation to the lung. PLoS One 7:e41329 |
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