The Cell and Vector Core (Core B) will provide stem and progenitor cells (human endothelial, hematopoietic, embryonic), reagents, and lentiviral vectors for investigators in all Projects, and for the Pilot and Feasibility Program. Core B will isolate rhesus and human endothelial progenitor cells (EPCs) from blood and vessels, co-culture rhesus and human EPC and hematopoietic stem cells (HSC), provide lentiviral vectors for transduction of HSC and EPC, and prepare cells for transplant for Project 1. Core B will also grow and cryopreserve renal precursors and EPCs, provide lentiviral vectors for transduction of renal precursors and EPC, and prepare cells for transplant for Project 2. For Project 3, the Core will provide human cells and lentiviral vectors, co-culture differentiated embryonic stem cells and EPC, and transduce cells and prepare for transplant (human HSC, EPC, embryonic stem cells). The Core will also provide cells and vectors to investigators funded through the Pilot and Feasibility Program.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Specialized Center (P50)
Project #
5P50HL085036-04
Application #
7670376
Study Section
Special Emphasis Panel (ZNS1)
Project Start
Project End
Budget Start
2008-09-01
Budget End
2009-08-31
Support Year
4
Fiscal Year
2008
Total Cost
$459,667
Indirect Cost
Name
University of California Davis
Department
Type
DUNS #
047120084
City
Davis
State
CA
Country
United States
Zip Code
95618
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