Abstract

The Tobacco Product Evaluation and Expose Core (Core B) will provide members of AHA Tobacco Regulation and Addiction Center (A-TRAC) the research capabilities to identify and evaluate tobacco product composition and constituents;to perform realistic tobacco product exposures in animal models such that delivery of tobacco products that replicates real world human exposures;to measure biomarkers of tobacco exposure;and to develop analytical techniques and approaches that improve our understanding of the complex relationship between markers of tobacco exposure and biomarkers of cardiovascular injury (see Core C). The Core will serve both the needs of Center projects and be an active research Core in its own right as it develops new and improved techniques that enhance the breadth and sensitivity of detection of tobacco product constituents and promotes better understanding of new and emerging tobacco products.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Specialized Center (P50)
Project #
5P50HL120163-02
Application #
8737961
Study Section
Special Emphasis Panel (ZRG1)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
2
Fiscal Year
2014
Total Cost
Indirect Cost

  Institution

Name
American Heart Association
Department
Type
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75231

  Publications

Riggs, Daniel W; Yeager, Ray A; Bhatnagar, Aruni (2018) Defining the Human Envirome: An Omics Approach for Assessing the Environmental Risk of Cardiovascular Disease. Circ Res 122:1259-1275
Fetterman, Jessica L; Weisbrod, Robert M; Feng, Bihua et al. (2018) Flavorings in Tobacco Products Induce Endothelial Cell Dysfunction. Arterioscler Thromb Vasc Biol 38:1607-1615
Ma, Jennie Z; Hart, Joy L; Walker, Kandi L et al. (2018) Perceived health risks of electronic nicotine delivery systems (ENDS) users: The role of cigarette smoking status. Addict Behav :
Wan, Ma; Bennett, Brian D; Pittman, Gary S et al. (2018) Identification of Smoking-Associated Differentially Methylated Regions Using Reduced Representation Bisulfite Sequencing and Cell type-Specific Enhancer Activation and Gene Expression. Environ Health Perspect 126:047015
Ko, Darae; Preis, Sarah R; Lubitz, Steven A et al. (2018) Relation of Orthostatic Hypotension With New-Onset Atrial Fibrillation (From the Framingham Heart Study). Am J Cardiol 121:596-601
Mead, Erin L; Cruz-Cano, Raul; Groom, Allison et al. (2018) Responses to cigarette health warning labels, harm perceptions and knowledge in a national sample of pregnant and non-pregnant women of reproductive age. Addict Behav 90:10-13
Kamimura, Daisuke; Cain, Loretta R; Mentz, Robert J et al. (2018) Cigarette Smoking and Incident Heart Failure: Insights From the Jackson Heart Study. Circulation 137:2572-2582
Nayor, Matthew; Enserro, Danielle M; Xanthakis, Vanessa et al. (2018) Comorbidities and Cardiometabolic Disease: Relationship With Longitudinal Changes in Diastolic Function. JACC Heart Fail 6:317-325
Hart, Joy L; Walker, Kandi L; Sears, Clara G et al. (2018) The 'state' of tobacco: Perceptions of tobacco among Appalachian youth in Kentucky. Tob Prev Cessat 4:
Olmedo, Pablo; Goessler, Walter; Tanda, Stefan et al. (2018) Metal Concentrations in e-Cigarette Liquid and Aerosol Samples: The Contribution of Metallic Coils. Environ Health Perspect 126:027010

Showing the most recent 10 out of 82 publications