As the U.S. HIV epidemic continues to unfold, injection drug use accounts for an ever increasing proportion of HIV infections. Current prevention efforts have failed to adequately slow the spread of HIV among injection drug users, Community interventions have been successful in promoting a wide variety of health behaviors but are only now beginning to be tried in efforts to prevent HIV. We propose to evaluate a multifocal community intervention to slow the spread of HIV among out-of-treatment injection drug users. The project combines the principles of community ethnography to identify and gain access to social networks of drug users, and diffusion theory to mobilize drug user's natural social networks around community norms for safer injection and safer sex. We will: . Evaluate the intervention's impact upon community norms for safer injection drug use and safer sex. . Examine the intervention's impact in promoting safer injection and safer sex. . Assess relationships between exposure to individual intervention components and safer behaviors. . Assess the extent to which peer support and peer communication mediate the effect of the intervention on study outcomes. . Estimate the effectiveness and cost-effectiveness of the intervention in averting new HIV infections. The evaluation of the intervention entails surveys of injection drug users conducted continuously in the intervention community (Sacramento) and comparison community (San Diego) before, during, and after implementation of the intervention in Sacramento. One thousand (1,000) survey respondents (500 each in Sacramento an San Diego) each year will be interviewed annually in years 1 through 4 of the study. The intervention, implemented in years 2 and 3, is designed to reach all injecting drug users in the community. The intervention consists of six interlocking components that can be implemented by a five person outreach team. The components include; 1) social network-targeted outreach; 2) a grassroots social network intervention designed to build community norms and peer support for risk reduction; 3) a high volume mobile needle-exchange; 4) an advocacy group organized by and for injection drug users; 5) specialized media targeted to drug users; 6) and a community advisory board composed of representatives of community agencies serving injection drug users to assure consistent dissemination of prevention messages. Data analysis will compare trends in community norms for safer injection and safe sex and preventive behaviors across cities to assess the effectiveness of the intervention.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Specialized Center (P50)
Project #
5P50MH042459-12
Application #
6242999
Study Section
Project Start
1997-09-30
Project End
1998-08-31
Budget Start
1996-10-01
Budget End
1997-09-30
Support Year
12
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Type
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Behrends, Czarina N; Li, Chin-Shang; Gibson, David R (2017) Decreased Odds of Injection Risk Behavior Associated With Direct Versus Indirect Use of Syringe Exchange: Evidence From Two California Cities. Subst Use Misuse 52:1151-1159
Dolcini, M Margaret; Catania, Joseph A; Harper, Gary W et al. (2013) Norms governing urban African American adolescents' sexual and substance-using behavior. J Adolesc 36:31-43
Bhattacharya, Gauri (2011) Global contexts, social capital, and acculturative stress: experiences of Indian immigrant men in New York City. J Immigr Minor Health 13:756-65
Bowleg, Lisa; Valera, Pamela; Teti, Michelle et al. (2010) Silences, gestures, and words: nonverbal and verbal communication about HIV/AIDS and condom use in black heterosexual relationships. Health Commun 25:80-90
White, Douglas B; Malvar, Grace; Karr, Jennifer et al. (2010) Expanding the paradigm of the physician's role in surrogate decision-making: an empirically derived framework. Crit Care Med 38:743-50
Gibson, David R; Zhang, Guili; Cassady, Diana et al. (2010) Effectiveness of HIV prevention social marketing with injecting drug users. Am J Public Health 100:1828-30
Dolcini, M Margaret; Grinstead Reznick, Olga A; Marin, Barbara V (2009) Investments in the future of behavioral science: the University of California, San Francisco, Visiting Professors Program. Am J Public Health 99 Suppl 1:S43-7
Bhattacharya, Gauri (2008) Acculturating Indian immigrant men in New York City: applying the social capital construct to understand their experiences and health. J Immigr Minor Health 10:91-101
Sucupira, Maria Cecilia Araripe; Caseiro, Marcos Montani; Alves, Katia et al. (2007) High levels of primary antiretroviral resistance genotypic mutations and B/F recombinants in Santos, Brazil. AIDS Patient Care STDS 21:116-28
White, Douglas B; Curtis, J Randall; Wolf, Leslie E et al. (2007) Life support for patients without a surrogate decision maker: who decides? Ann Intern Med 147:34-40

Showing the most recent 10 out of 308 publications