This project develops, analyses, and tests neural network models of decision-making, perceptual choice, memory recall, and attention, focusing on the relationship of conflict detection to control. The concepts of conflict and control will be operationalized in these models, and then numerical simulations and analytical methods of dynamical systems theory will be used to study the models, predict their behavior, and delineate parameter ranges that best correspond to empirical data. Such models formalize and sharpen the major Center hypotheses, complementing the experimental work of Projects 1-6. Success in this effort will lead to a more precise understanding of the mechanisms that govern the allocation of cognitive control, and their neural implementation.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Specialized Center (P50)
Project #
5P50MH062196-02
Application #
6506742
Study Section
Special Emphasis Panel (ZMH1)
Project Start
2001-09-01
Project End
2002-08-31
Budget Start
Budget End
Support Year
2
Fiscal Year
2001
Total Cost
Indirect Cost
Name
Princeton University
Department
Type
DUNS #
002484665
City
Princeton
State
NJ
Country
United States
Zip Code
08544
Aston-Jones, G; Waterhouse, B (2016) Locus coeruleus: From global projection system to adaptive regulation of behavior. Brain Res 1645:75-8
Casey, B J (2015) Beyond simple models of self-control to circuit-based accounts of adolescent behavior. Annu Rev Psychol 66:295-319
Freestone, David M; Balc?, Fuat; Simen, Patrick et al. (2015) Optimal response rates in humans and rats. J Exp Psychol Anim Learn Cogn 41:39-51
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Kalwani, Rishi M; Joshi, Siddhartha; Gold, Joshua I (2014) Phasic activation of individual neurons in the locus ceruleus/subceruleus complex of monkeys reflects rewarded decisions to go but not stop. J Neurosci 34:13656-69
Teslovich, Theresa; Mulder, Martijn; Franklin, Nicholas T et al. (2014) Adolescents let sufficient evidence accumulate before making a decision when large incentives are at stake. Dev Sci 17:59-70
Karmiloff-Smith, Annette; Casey, B J; Massand, Esha et al. (2014) Environmental and Genetic Influences on Neurocognitive Development: The Importance of Multiple Methodologies and Time-Dependent Intervention. Clin Psychol Sci 2:628-637
Balc?, Fuat; Simen, Patrick (2014) Decision processes in temporal discrimination. Acta Psychol (Amst) 149:157-68
Kool, Wouter; Botvinick, Matthew (2014) A labor/leisure tradeoff in cognitive control. J Exp Psychol Gen 143:131-41

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