Abstract

This application requests five years of support to establish an NIMH Center for Intervention Development and Applied Research (""""""""CIDAR"""""""") entitled """"""""Vulnerability to Progression in Schizophrenia"""""""". The Operations and Clinical Assessment (OCA) Core (Seidman, PI) is responsible for location and recruitment of research participants, selection of all clinical (e.g., diagnostic and neuropsychological) instruments, training and quality control of the use of the instruments, and supervision of recruiters, diagnosticians, raters and of testers. The OCA is responsible for maintaining the subject flow, maintaining all records of study participants and ensuring that IRB, HIPAA and other regulatory procedures are followed. The OCA is also responsible for data management and statistical analysis. The OCA is the operational hub of a complex study involving five other

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Specialized Center (P50)
Project #
5P50MH080272-04
Application #
8136030
Study Section
Special Emphasis Panel (ZMH1)
Project Start
2010-09-01
Project End
2012-08-31
Budget Start
2010-09-01
Budget End
2011-08-31
Support Year
4
Fiscal Year
2010
Total Cost
$240,852
Indirect Cost

  Institution

Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02215

  Publications

Woodberry, Kristen A; Seidman, Larry J; Bryant, Caitlin et al. (2018) Treatment Precedes Positive Symptoms in North American Adolescent and Young Adult Clinical High Risk Cohort. J Clin Child Adolesc Psychol 47:69-78
Ohtani, Toshiyuki; Del Re, Elisabetta; Levitt, James J et al. (2018) Progressive symptom-associated prefrontal volume loss occurs in first-episode schizophrenia but not in affective psychosis. Brain Struct Funct 223:2879-2892
Konishi, Jun; Del Re, Elisabetta C; Bouix, Sylvain et al. (2018) Abnormal relationships between local and global brain measures in subjects at clinical high risk for psychosis: a pilot study. Brain Imaging Behav 12:974-988
Stowkowy, Jacqueline; Liu, Lu; Cadenhead, Kristin S et al. (2018) Exploration of clinical high-risk dropouts. Schizophr Res 195:579-580
Hamoda, Hesham M; Makhlouf, A T; Fitzsimmons, J et al. (2018) Abnormalities in thalamo-cortical connections in patients with first-episode schizophrenia: a two-tensor tractography study. Brain Imaging Behav :
Seitz, Johanna; Rathi, Yogesh; Lyall, Amanda et al. (2018) Alteration of gray matter microstructure in schizophrenia. Brain Imaging Behav 12:54-63
Kline, Emily; Hendel, Victoria; Friedman-Yakoobian, Michelle et al. (2018) A comparison of neurocognition and functioning in first episode psychosis populations: do research samples reflect the real world? Soc Psychiatry Psychiatr Epidemiol :
Hampton, Joya N; Trotman, Hanan D; Addington, Jean et al. (2018) The relation of atypical antipsychotic use and stress with weight in individuals at clinical high risk for psychosis. Stress Health 34:591-600
Saito, Yukiko; Kubicki, Marek; Koerte, Inga et al. (2018) Impaired white matter connectivity between regions containing mirror neurons, and relationship to negative symptoms and social cognition, in patients with first-episode schizophrenia. Brain Imaging Behav 12:229-237
Chung, Yoonho; Haut, Kristen M; He, George et al. (2017) Ventricular enlargement and progressive reduction of cortical gray matter are linked in prodromal youth who develop psychosis. Schizophr Res 189:169-174

Showing the most recent 10 out of 156 publications